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Commit b4ad752f authored by HouTeng Chan's avatar HouTeng Chan
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<p>ADD LZF PART HERE </p>
<h3>Developing an Interactive Educational Tool for Teenagers</h3>
<h4>Introduction: Addressing the Challenge of Abstract Concepts in Synthetic Biology</h4>
<p>The concepts and principles of synthetic biology are often abstract and difficult for teenagers to grasp. To address this, we drew a parallel between synthetic biology and modular programming, breaking down biological components into block-like modules. Our goal is to design educational software that mirrors modular programming, helping teenagers understand synthetic biology by simplifying it into building blocks. This approach aims to make synthetic biology more accessible and widely understood within the adolescent community.</p>
<h4>Concept Development: Building the Foundation</h4>
<p>After discussing with Codemao, a company specializing in modular programming, through an online meeting, we successfully developed a preliminary concept for a popular science software. This software was designed to simplify the understanding of synthetic biology by presenting it in a way that teenagers can easily interact with and explore.</p>
<div style="text-align: center;">
<img src="https://static.igem.wiki/teams/5187/wiki-inclusivity-fig/inclu1.png" alt="ibd_figure" class="shadowed-image" style="width: 60%; max-width: 600px;">
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<h4>Software Design: Simplifying Complex Concepts</h4>
<p>The software is divided into two key panels:</p>
<ul>
<li><b>Component Building Panel</b></li>
<li><b>Control Panel</b></li>
</ul>
<p>The content is split into three sections:</p>
<ul>
<li><b>Basic Knowledge Learning</b></li>
<li><b>Basic Component Creation</b></li>
<li><b>Free Design</b></li>
</ul>
<h4>Teaching Key Concepts</h4>
<p>The software first introduces users to the central dogma of biology and key laboratory techniques, such as DNA replication, transcription, translation, and reverse transcription. For instance, in the case of DNA replication, the component building panel provides essential materials like dNTPs, primers, template DNA, and DNA polymerase. Guided by shadows and arrows, users are led to build a PCR reaction. On the control panel, users then program the denaturation, annealing, and extension cycles in a modular format, unlocking the PCR process as they follow the instructions.</p>
<p>This approach allows us to demonstrate commonly used synthetic biology laboratory techniques, while also teaching fundamental biological knowledge rooted in the central dogma.</p>
<div style="text-align: center;">
<img src="https://static.igem.wiki/teams/5187/wiki-inclusivity-fig/inclu2.png" alt="ibd_figure" class="shadowed-image" style="width: 60%; max-width: 600px;">
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<h4>Basic Component Creation: Building Core Synthetic Biology Elements</h4>
<p>In the <b>Basic Component Production</b> section, we focus on two classic synthetic biology elements: the <b>switch</b> and oscillator. A switch consists of a pair of mutually repressed promoters and genes, showcasing bistability under different inducer concentrations. Using the component building and control panels, users can construct and visualize this process, unlocking the switch as a new basic component for further use.</p>
<p>Similarly, the construction of an <b>oscillator</b> can be demonstrated using the same approach. In this case, the switch and oscillator represent the equivalent of conditional and loop statements in programming languages. By encapsulating these components as basic elements, the software conveys the modular design concept of synthetic biology, much like circuit design in electronics. Additionally, the inclusion of logic gates will enrich the educational experience, allowing users to deepen their understanding of biological logic systems.</p>
<div style="text-align: center;">
<img src="https://static.igem.wiki/teams/5187/wiki-inclusivity-fig/inclu3.png" alt="ibd_figure" class="shadowed-image" style="width: 60%; max-width: 600px;">
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<h4>Encouraging Creativity: Free Design and Project Visualization</h4>
<p>In the <p>Free</p> Design section, users can select common chassis organisms and design synthetic biology projects using components they have built or defined. This feature not only aids iGEM teams in visualizing their projects but also opens the door to organizing synthetic biology design competitions for teenagers. By giving young users the freedom to experiment with their own designs, the software fosters creativity and engagement.</p>
<div style="text-align: center;">
<img src="https://static.igem.wiki/teams/5187/wiki-inclusivity-fig/inclu4.png" alt="ibd_figure" class="shadowed-image" style="width: 40%; max-width: 400px;">
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