Update model.html

wiki/pages/model.html

@@ -40,7 +40,7 @@
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     <ul>
       <li><a href="#description">General Description of Modeling</a></li>
-      <li><a href="#topic1">Topic1</a></li>
+      <li><a href="#topic1">Compartment Model for Muscone Inhalation</a></li>
       <li><a href="#topic2">Topic2</a></li>
       <li><a href="#topic3">Topic3</a></li>
       <li><a href="#topic4">Topic4</a></li>
@@ -60,42 +60,61 @@
       <hr>
       <p>Our model serves three main purposes:</p>
       <ol>
-        <li><strong>Quantitative Description of Project Design</strong>: It aids readers in understanding the processes
-          involved in our project design, enabling a better narration of our story.</li>
-        <li><strong>Computational Methods for Project Engineering</strong>: If the project proceeds, the model can
-          assist in determining parameters during project implementation, reducing computational effort during
-          experimentation.</li>
-        <li><strong>Reduction of Wet Lab Experiment Scale</strong>: The model can predict the behavior of the system
-          under study, helping to eliminate unnecessary trials in wet lab experiments.</li>
+        <li><strong>Quantitative Description of Project Design</strong>: It aids readers in understanding the
+          processes involved in our project design, enabling a better narration of our story.</li>
+        <li><strong>Computational Methods for Project Engineering</strong>: If the project proceeds, the model
+          can assist in determining parameters during project implementation, reducing computational effort
+          during experimentation.</li>
+        <li><strong>Reduction of Wet Lab Experiment Scale</strong>: The model can predict the behavior of the
+          system under study, helping to eliminate unnecessary trials in wet lab experiments.</li>
       </ol>
-      <p>Our model is divided into four interconnected parts, representing the inhalation of muscone, its binding to
-        receptors, intracellular signal transduction and lactic acid secretion triggered by receptor activation, and the
-        absorption of lactic acid. These models provide a comprehensive understanding of the project and yield valuable
-        computational results.</p>
+      <p>Our model is divided into four interconnected parts, representing the inhalation of muscone, its binding
+        to receptors, intracellular signal transduction and lactic acid secretion triggered by receptor
+        activation, and the absorption of lactic acid. These models provide a comprehensive understanding of the
+        project and yield valuable computational results.</p>
     </div>
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-      <img src="https://static.igem.wiki/teams/5187/figure/ibd-figure.jpg" alt="ibd_figure" class="shadowed-image">
+      <img src="https://static.igem.wiki/teams/5187/figure/ibd-figure.jpg" alt="ibd_figure"
+                class="shadowed-image">
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     <div class="col-lg-12">
       <h2 id="topic1">
-        <h2>Topic1</h2>
+        <h2>Compartment Model for Muscone Inhalation</h2>
         <hr>
-        <p>Tsinghua University is a public university in Haidian, Beijing. It is affiliated with and funded by
-          the Ministry of Education of China. The university is part of Project 211, Project 985, and the
-          Double First-Class Construction. It is also a member of the C9 League. Tsinghua University's campus
-          is situated in northwest Beijing, on the site of the former imperial gardens of the Qing dynasty.
-          Currently, the university has 21 schools and 59 departments, with faculties in science, engineering,
-          humanities, law, medicine, history, philosophy, economics, management, education and art.</p>
-        <p>Notable alumni who have held senior positions in Chinese politics include current general secretary
-          and president of China, Xi Jinping, former general secretary and president of China Hu Jintao,
-          former chairman of the National People's Congress Wu Bangguo, former premier Zhu Rongji, and the
-          former first vice premier Huang Ju. This also includes politicians like Wu Guanzheng, former
-          governor of the People's Bank of China Zhou Xiaochuan, former minister of finance Lou Jiwei, general
-          Sun Li-jen, Liang Qichao, and more. Since 2016, Tsinghua graduates who have political prominence are
-          disproportionately greater in number than graduates of other famous universities.</p>
+        <h3>Model Description</h3>
+        <p>The main focus of our project is the use of muscone as a signaling molecule to activate engineered
+          bacteria in the gut for therapeutic purposes. Therefore, it is crucial to provide a quantitative
+          description and computational support for the diffusion of muscone in the body. This model describes
+          the entire process from the inhalation of muscone to its increased concentration in the intestinal
+          tract. We will establish a multi-compartment model that includes the following main processes:</p>
+        <ol>
+          <li><strong>Inhalation Process</strong>: Muscone is inhaled in the form of an aerosol into the
+            lungs.</li>
+          <li><strong>Pulmonary Process</strong>: Muscone distributes in the alveoli and may be exhaled,
+            adhered to, or permeated into the microvessels.</li>
+          <li><strong>Adhesion Process</strong>: A portion of muscone adheres to the respiratory mucosa and
+            then diffuses into the systemic circulation.</li>
+          <li><strong>Alveolar Microvessel Process</strong>: Muscone permeates into the alveolar microvessels
+            and gradually enters the systemic circulation.</li>
+          <li><strong>Systemic Circulation Process</strong>: Muscone distributes in the systemic circulation
+            and is transported to various parts of the body through the bloodstream.</li>
+          <li><strong>Intestinal Process</strong>: Muscone enters the target intestine through the mesenteric
+            microvascular network, where its concentration begins to increase.</li>
+        </ol>
+        <p>TODO:Insert design diagram</p>
+        <p>Corresponding to the above processes, five compartments need to be established for simulation, where
+          $t$ represents the time variable:</p>
+        <ol>
+          <li><strong>Compartment 0</strong>(Alveolar Space, A): $Q_A(t)$ represents the amount of muscone in
+            the alveoli (mg).</li>
+          <li><strong>Compartment 1</strong></li>
+          <li><strong>Compartment 2</strong></li>
+          <li><strong>Compartment 3</strong></li>
+          <li><strong>Compartment 4</strong></li>
+        </ol>
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