Skip to content
Snippets Groups Projects
Commit f1102294 authored by Liliana Sanfilippo's avatar Liliana Sanfilippo
Browse files

home

parent 40d0f821
No related branches found
No related tags found
No related merge requests found
......@@ -54,4 +54,19 @@
background-size: 100% auto;
background-repeat: no-repeat;
padding: 0 !important;
}
.button-x{
align-items: center;
display: flex;
align-self: center;
}
.button-x button{
margin: auto;
padding: 10px;
border-radius: 10px;
background-color: var(--text-primary);
color: var(--ourbeige)
}
\ No newline at end of file
......@@ -7,7 +7,6 @@ import { useTabNavigation } from "../utils/TabNavigation";
import { H5 } from "../components/Headings";
import PreCyse from "../components/precyse";
import { useNavigation } from "../utils";
import SVGComponentOne from "./Home Folder/svg-one";
export function Home() {
useTabNavigation();
......@@ -61,6 +60,19 @@ export function Home() {
</div>
</div>
<img src="https://static.igem.wiki/teams/5247/landing-page/lp-2.svg"/>
<div className="row">
<div className="col button-x">
<button onClick={() => goToPageAndScroll("Approach2H", "/description")} > Lung-Specific Lipid Nanoparticle</button>
</div>
<div className="col button-x">
<button onClick={() => goToPageAndScroll("Approach1H", "/description")} > Next-Generation Prime Editing Technology
</button>
</div>
</div>
<div className="row mt-4">
<div className="col" id="erstecol">
<div className="col">
......
......@@ -288,7 +288,7 @@ export function Description() {
<p>All these challenges complicate the work with LNPs and present scientists with a great challenge, which makes working with LNPs even more important to find solutions.</p>
</Collapsible>
<br/>
<div className='row align-items-center'>
<div id="airbuddy-hook" className='row align-items-center'>
<p>To optimize AirBuddy for pulmonary delivery, we collaborated extensively with several experts, including <a onClick={() => goToPagesAndOpenTab('weber', '/human-practices')}>Prof. Weber, Dr. Große-Onnebrink</a> and <a onClick={() => goToPagesAndOpenTab('kolonkofirst', '/human-practices')}>Dr. Kolonko</a> as medical experts, <a onClick={() => goToPagesAndOpenTab('kristian', '/human-practices')}>Prof. Dr. Müller</a>, <a onClick={() => goToPagesAndOpenTab('radukic', '/human-practices')}>Dr. Radukic</a>, <a onClick={() => goToPagesAndOpenTab('moorlach', '/human-practices')}>Benjamin Moorlach</a> and the <a onClick={() => goToPagesAndOpenTab('biophysik', '/human-practices')}>Physical and Biophysical Chemistry working group</a> as academic experts form Bielefeld University and FH Bielefeld as well as <a onClick={() => goToPagesAndOpenTab('corden', '/human-practices')}>Corden Pharma</a> and <a onClick={() => goToPagesAndOpenTab('rnhale', '/human-practices')}>RNhale</a> as industrial experts. Throughout the <a onClick={() => goToPagesAndOpenTab('delivery head', '/engineering')}>development process</a>, we tested two commercially available kits: the <strong>Cayman Chemical LNP Exploration Kit (LNP-102)</strong> and the <strong>Corden Pharma LNP Starter Kit #2</strong>. While the Cayman kit demonstrated limited transfection efficiency, the Corden Pharma formulation significantly enhanced cellular uptake in lung tissues. Building on this, we integrated the <strong>SORT LNP</strong> method based on Wang's research <SupScrollLink label="1"/> , making our nanoparticles lung-specific. Additionally, we employed the <strong>spray-drying technique</strong> in cooperation with RNhale <SupScrollLink label="2"/> to improve the stability of our LNP, ensuring that it withstands the inhalation process without degradation. This stability is crucial for the efficient delivery of mRNA into lung epithelial cells, where PrimeGuide can effectively perform genome editing.</p>
<img src="https://static.igem.wiki/teams/5247/delivery/big-plan-inhalation-teil-del.webp"/>
</div>
......
0% Loading or .
You are about to add 0 people to the discussion. Proceed with caution.
Finish editing this message first!
Please register or to comment