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Commit 6a51d61c authored by Huang Lintaihui's avatar Huang Lintaihui
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</ul>
<h3 id='weakness'><strong>Weakness</strong></h3>
<ul>
<li>Our genetic circuit could be more manageable and more streamlined due to the combinations of various logic
gates;</li>
<li>Our genetic circuit is not streamlined enough and there may be difficulties in transferring the complete
circuit into an E. coli;</li>
<li>The efficiency, stability, and orthogonality of genetic circuits remained to be enhanced to avoid unwanted
crosstalk;</li>
<li>Lack of practical application implementation though with rich application prospectives.</li>
......@@ -87,7 +87,8 @@
<h3 id='pay-attention-to-other-biological-gates'>Pay attention to other biological gates</h3>
<ul>
<li><strong>Diverse Gate Types</strong>: Incorporate a variety of logic gates (AND, OR, NOR, NOT, XOR, etc.)
into the system to ensure that the genetic circuits can accomplish larger systems.</li>
into the system to ensure that our project can perform any logical functions and support the integration of
diverse gate functions, such as cell memory.</li>
<li><strong>Cross-compatibility with Host Systems</strong>: Design similar programmable components across
various host biological systems to enhance the component&#39;s versatility, laying the foundation for
building biological logic circuits.</li>
......@@ -107,9 +108,9 @@
</ul>
<h2 id='reference'><strong>Reference</strong></h2>
<p>[1] Singh V. (2014). Recent advances and opportunities in synthetic logic gates engineering in living
cells. <em>Systems and synthetic biology</em>, <em>8</em>(4), 271282.</p>
<p> [2] Wang, B., Kitney, R., Joly, N. <em>et al.</em> Engineering modular and orthogonal genetic logic gates for
robust digital-like synthetic biology. <em>Nat Commun</em> <strong>2</strong>, 508 (2011).</p>
cells. <em>Systems and synthetic biology</em>, <em>8</em>(4), 271-282.</p>
<p> [2] Wang, B., Kitney, R., Joly, N. <em>et al.</em> Engineering modular and orthogonal genetic logic gates for
robust digital-like synthetic biology. <em>Nat Commun</em> <strong>2</strong>, 508 (2011).</p>
<p> [3] Xia, P., Ling, H., Foo, J. L., &amp; Chang, M. W. (2019). Synthetic genetic circuits for programmable
biological functionalities. <em>Biotechnology Advances</em>, <em>37</em>(6), 107393.</p>
</div>
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