<pclass="small-text">[1] Kaplan GG. The global burden of IBD: from 2015 to 2025. Nat Rev Gastroenterol Hepatol. 2015 Dec;12(12):720-7. doi: 10.1038/nrgastro.2015.150. Epub 2015 Sep 1. PMID: 26323879.</p>
<pclass="small-text">[2] Faye AS, Colombel JF. Aging and IBD: A New Challenge for Clinicians and Researchers. Inflamm Bowel Dis. 2022 Jan 5;28(1):126-132. doi: 10.1093/ibd/izab039. PMID: 33904578.</p>
<pclass="small-text">[3] Camarca A, Rotondi Aufiero V, Mazzarella G. Role of Regulatory T Cells and Their Potential Therapeutic Applications in Celiac Disease. Int J Mol Sci. 2023 Sep 22;24(19):14434. doi: 10.3390/ijms241914434. PMID: 37833882; PMCID: PMC10572745.</p>
<pclass="small-text">[4] Guan Q. A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease. J Immunol Res. 2019 Dec 1;2019:7247238. doi: 10.1155/2019/7247238. PMID: 31886308; PMCID: PMC6914932.Fan Y, Lyu B. [Research frontier of inflammatory bowel disease]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2019 May 25;48(3):334-341. Chinese. doi: 10.3785/j.issn.1008-9292.2019.06.15. PMID: 31496167; PMCID: PMC8800741.</p>
<pclass="small-text">[5] Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. Epub 2023 Aug 9. PMID: 37558878; PMCID: PMC10725186.</p>
<pclass="small-text">[6] Knight SC. Dendritic Cell-T-Cell Circuitry in Health and Changes in Inflammatory Bowel Disease and Its Treatment. Dig Dis. 2016;34(1-2):51-7. doi: 10.1159/000442926. Epub 2016 Mar 16. PMID: 26982806; PMCID: PMC5022659.</p>
<pclass="small-text">[7] Wu X, Yu Y, Wang M, Dai D, Yin J, Liu W, Kong D, Tang S, Meng M, Gao T, Zhang Y, Zhou Y, Guan N, Zhao S, Ye H. AAV-delivered muscone-induced transgene system for treating chronic diseases in mice via inhalation. Nat Commun. 2024 Feb 6;15(1):1122. doi: 10.1038/s41467-024-45383-z. PMID: 38321056; PMCID: PMC10847102.</p>
<pclass="small-text">[8] Johns Hopkins Medicine ,Inflammatory Bowel Disease (IBD), https://www.hopkinsmedicine.org/health/conditions-and-diseases/inflammatory-bowel-disease
<pstyle="font-size: 0.7em;">[1] Kaplan GG. The global burden of IBD: from 2015 to 2025. Nat Rev Gastroenterol Hepatol. 2015 Dec;12(12):720-7. doi: 10.1038/nrgastro.2015.150. Epub 2015 Sep 1. PMID: 26323879.</p>
<pstyle="font-size: 0.7em;">[2] Faye AS, Colombel JF. Aging and IBD: A New Challenge for Clinicians and Researchers. Inflamm Bowel Dis. 2022 Jan 5;28(1):126-132. doi: 10.1093/ibd/izab039. PMID: 33904578.</p>
<pstyle="font-size: 0.7em;">[3] Camarca A, Rotondi Aufiero V, Mazzarella G. Role of Regulatory T Cells and Their Potential Therapeutic Applications in Celiac Disease. Int J Mol Sci. 2023 Sep 22;24(19):14434. doi: 10.3390/ijms241914434. PMID: 37833882; PMCID: PMC10572745.</p>
<pstyle="font-size: 0.7em;">[4] Guan Q. A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease. J Immunol Res. 2019 Dec 1;2019:7247238. doi: 10.1155/2019/7247238. PMID: 31886308; PMCID: PMC6914932.Fan Y, Lyu B. [Research frontier of inflammatory bowel disease]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2019 May 25;48(3):334-341. Chinese. doi: 10.3785/j.issn.1008-9292.2019.06.15. PMID: 31496167; PMCID: PMC8800741.</p>
<pstyle="font-size: 0.7em;">[5] Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. Epub 2023 Aug 9. PMID: 37558878; PMCID: PMC10725186.</p>
<pstyle="font-size: 0.7em;">[6] Knight SC. Dendritic Cell-T-Cell Circuitry in Health and Changes in Inflammatory Bowel Disease and Its Treatment. Dig Dis. 2016;34(1-2):51-7. doi: 10.1159/000442926. Epub 2016 Mar 16. PMID: 26982806; PMCID: PMC5022659.</p>
<pstyle="font-size: 0.7em;">[7] Wu X, Yu Y, Wang M, Dai D, Yin J, Liu W, Kong D, Tang S, Meng M, Gao T, Zhang Y, Zhou Y, Guan N, Zhao S, Ye H. AAV-delivered muscone-induced transgene system for treating chronic diseases in mice via inhalation. Nat Commun. 2024 Feb 6;15(1):1122. doi: 10.1038/s41467-024-45383-z. PMID: 38321056; PMCID: PMC10847102.</p>
<pstyle="font-size: 0.7em;">[8] Johns Hopkins Medicine ,Inflammatory Bowel Disease (IBD), https://www.hopkinsmedicine.org/health/conditions-and-diseases/inflammatory-bowel-disease