<h3>Tetrathionate Sensing Colonization System: High efficiency in treatment</h3>
<p>We selected the signaling pathway of the sensor, designed by a previous team, that can detect tetrathionate (a marker of IBD) and we connected the ALS3 adhesion protein downstream. When the system detects the marker of IBD, Saccharomyces cerevisiae can adhere to the intestinal tract by expressing the ALS3 protein, achieving the colonization of the engineered strain. Future iGEM may refer our design when considering colonization in guts for other diseases.</p>