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Commit 9ab87827 authored by Jing Hua's avatar Jing Hua
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......@@ -87,7 +87,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
<p>
<h2 class='animate wiki-title2'>Cycle 1: Identifying the problem</h2>
<h3 class='black'>I: What problems do we identify and what problems do we try to solve?</h3>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em">I: What problems do we identify and what problems do we try to solve?</h3>
<p>
In the beginning, we faced the problem of identifying a theme. We held weekly brainstorming sessions to share
our ideas and concepts. But this led to the problem that many assumptions and designs require context, and you
......@@ -95,7 +95,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
the problem and look for the pain points of the problem and, at the same time, identify the problem we want to
solve? Is the problem really necessary to exist?
</p>
<br>
<p>We learned from books about the threat of pathogenic bacteria to the human body, especially to susceptible
people such as the elderly, pregnant women, and immunocompromised people, which led our team to propose a
general direction: prevention of pathogenic bacteria. We plan to solve the problem in two ways: 1. We have
......@@ -103,9 +103,9 @@ teams on difficult problems that you can more easily solve together.{% endblock
these two routes of infection by looking for respiratory and critical care physicians and gastroenterologists.
2. We will release a questionnaire to the public to find out what they know about pathogens. 3. What are the
measures that are currently being taken by people to prevent pathogens.</p>
<h3 class='animate wiki-title3'>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em">
D: Surveys and interviews</h3>
<h3>Questionnaire on public awareness of pathogenic bacteria</h3>
<h3 style="color: #bf9bf1;">Questionnaire on public awareness of pathogenic bacteria</h3>
<p>Although we have learned from books about the threat of pathogenic bacteria to human beings, especially the
threat of pathogenic bacteria to the elderly, pregnant women, immunocompromised and other susceptible groups, we
are not sure about the public's understanding of pathogenic bacteria and the degree of awareness of prevention,
......@@ -128,11 +128,11 @@ teams on difficult problems that you can more easily solve together.{% endblock
<p>Knowing the public's awareness of pathogenic bacteria, we will visit community health centers to continue to
understand the situation of pathogenic bacteria in the community and work towards further development of the
project.</p>
<h4>Interview with Dr. SWH</h4>
<figure class='figure imgbox center-block'>
<img src='https://static.igem.wiki/teams/5248/human-practices/integrated-human-practices/huxik.jpg'
<img src='https://static.igem.wiki/teams/5248/human-practices/integrated-human-practices/shekan.jpg'
class='figure-img img-fluid rounded' alt='...'>
<figcaption class='figure-caption text-center'>Figure 2:呼吸科
<figcaption class='figure-caption text-center'>Figure 2:
</figcaption>
</figure>
......@@ -144,6 +144,13 @@ teams on difficult problems that you can more easily solve together.{% endblock
thought that in the process of elimination, the pathogenic bacteria gradually develop drug resistance, and the
original means of elimination is not effective against them, so we thought whether biological control is better
than chemical and physical methods.</p>
<h4>Interview with Dr. Guo Lihua, Department of Respiratory and Critical Care Medicine</h4>
<figure class='figure imgbox center-block'>
<img src='https://static.igem.wiki/teams/5248/human-practices/integrated-human-practices/huxik.jpg'
class='figure-img img-fluid rounded' alt='...'>
<figcaption class='figure-caption text-center'>Figure 3:asas
</figcaption>
</figure>
<p>Combined with the information we found on the internet, we realized that one of the treatment directions of
respiratory medicine is to treat respiratory diseases caused by pathogenic bacterial and viral infections. We
......@@ -165,6 +172,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
transmission, another mode of transmission of pathogens, so we will go to the Gastroenterology Department to
find a Gastroenterologist to learn more about fecal-oral transmission so that we can determine the direction of
our project.</p>
<p>Interview with Dr. Sun, Gastroenterologist</p>
<p>The Department of Gastroenterology mainly treats digestive diseases, and one of the directions of treatment is
about treating infectious diarrhea, which is mainly caused by pathogens infecting other people through
fecal-oral transmission, and we would like to know about the effects of fecal-oral transmission on human body,
......@@ -172,14 +180,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
the hope of understanding about the effects of pathogens through fecal-oral transmission and how to prevent them
from infecting the population through fecal-oral transmission. Fecal-oral transmission infects people.</p>
<span>A: For fecal-oral transmission, what should we do to prevent pathogenic infections? </span>
<span>Q: Preventing infectious diseases involves controlling the source of infection, cutting off the means of
transmission, and protecting susceptible people.</span>
<h3 class='animate wiki-title3'>E: Determining the direction of the project</h3>
{% include 'pages/hp-dialogue-1.html' %}
<p>Through public questionnaires and interviews with stakeholders such as community health, respiratory
physicians, gastroenterologists, etc., we learned that the public's understanding of pathogenic bacteria is that
for pathogenic infections caused by airborne droplet transmission, masks can be worn to reduce the risk of
......@@ -191,7 +192,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
can stabilize their existence in a specific place, preventing pathogenic bacteria from invading and surviving,
and maintaining the safety of the environment, so as to achieve the effect of preventive biocontrol.</p>
<h3 class='animate wiki-title3'>A: Planning what to do next</h3>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em">A: Planning what to do next</h3>
<p>
Eventually, we decided to focus on the prevention of environmental pathogens as the theme of our project, which
......@@ -203,13 +204,13 @@ teams on difficult problems that you can more easily solve together.{% endblock
<h2 class='animate wiki-title2'>
Cycle 2: Experimental design</h2>
<h3 class='animate wiki-title3'>I: How should we design our experiment?</h3>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em">I: How should we design our experiment?</h3>
<p> After we decided to prevent pathogenic bacteria in the environment, we started to think about how to prevent
pathogenic bacteria in the environment and finally we planned to inhibit pathogenic bacteria in the
environment by modifying beneficial bacteria. We used E. coli Nissle 1917.
<h3 class='animate wiki-title3'> D: Interviews and recommendations</h3>
environment by modifying beneficial bacteria. We used E. coli Nissle 1917.</p>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em"> D: Interviews and recommendations</h3>
</p>
<p> In order to find out what other shortcomings there were in the experiment, we met with Zhou Kai, the head of
the Bacterial Drug Resistance Monitoring and Quality Control Center of Shenzhen People's Hospital, and
exchanged ideas about the design of the project, and he gave us a few suggestions:</p>
......@@ -235,7 +236,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
</figcaption>
</figure>
<h3 class='animate wiki-title3'> E&A: Adaptation of experimental design</h3>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em"> E&A: Adaptation of experimental design</h3>
<p>Based on our interaction with Director Kai Zhou, we have new ideas on how to reduce the risk of horizontal
......@@ -250,7 +251,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
mindset.</span>
</p>
<h2 class='animate wiki-title2' data-animate='zoomIn'>Cycle 3: Product Forms</h2>
<h3 class='animate wiki-title3' data-animate='zoomIn'>I: What product form do we want to present in the future?
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em"> I: What product form do we want to present in the future?
</h3>
<p>Considering the application of the project in practical scenarios, we first need to consider the form of the
product, our initial idea is to make it into the form of disinfection products, in order to make clear whether
......@@ -258,7 +259,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
Chief Scientist of Shenzhen Andover Disinfection Hi-Tech Company Limited, the Shenzhen People's Hospital
Disinfection Center Apparatus Disinfection Doctor, hope that from their professional perspective, what else do
we need to pay attention to?</p>
<h3 class='animate wiki-title3' data-animate='zoomIn'>D: Interviews and consultations</h3>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;"> D: Interviews and consultations</h3>
<figure class='figure imgbox center-block'>
<img src='https://static.igem.wiki/teams/5248/human-practices/integrated-human-practices/icu.jpg'
......@@ -321,8 +322,7 @@ teams on difficult problems that you can more easily solve together.{% endblock
there are still many problems to be solved in producing disinfection products biologically. There is a need to
consider safety issues and environmental issues that do not affect the environment.
</p>
<h3 class='animate wiki-title3' data-animate='zoomIn'>E&A: Interview Summary and Future Goals</h3>
<h3 class='animate wiki-title3' data-animate='zoomIn' style="color: black;font-size:2em"> E&A: Interview Summary and Future Goals</h3>
<p>Through communication with experts, we understand that there are many issues to consider if we want to apply
the project to reality, and in response to the advice given by experts, we have designed suicide switches to
reduce the risk of the release of engineered bacteria in the environment and to safeguard human safety, in
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