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2023 Competition
MIT
Commits
7d5cbf7c
Commit
7d5cbf7c
authored
1 year ago
by
Katie Spivakovsky
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updates
parent
a9a2578e
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Pipeline
#242962
passed
1 year ago
Stage: build
Stage: deploy
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3 changed files
static/scripts/functions.js
+2
-2
2 additions, 2 deletions
static/scripts/functions.js
wiki/pages/contribution.html
+37
-35
37 additions, 35 deletions
wiki/pages/contribution.html
wiki/pages/experiments.html
+345
-16
345 additions, 16 deletions
wiki/pages/experiments.html
with
384 additions
and
53 deletions
static/scripts/functions.js
+
2
−
2
View file @
7d5cbf7c
...
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@@ -192,8 +192,8 @@ if (window.location.href.indexOf('engineering') > -1) {
/* EXPERIMENTS PAGE */
if
(
window
.
location
.
href
.
indexOf
(
'
experiments
'
)
>
-
1
)
{
$
(
'
p
'
).
each
(
function
()
{
// initially hide all the detailed info
if
(
this
.
id
!=
'
all-protocols
'
)
{
$
(
'
div
'
).
each
(
function
()
{
// initially hide all the detailed info
if
(
this
.
id
.
indexOf
(
'
info
'
)
>
-
1
)
{
$
(
this
).
animate
({
height
:
'
toggle
'
})
...
...
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wiki/pages/contribution.html
+
37
−
35
View file @
7d5cbf7c
{% extends "layout.html" %}
{% block title %}Contribution{% endblock %}
{% block lead %}Make a useful contribution for future iGEM teams. Use this page to document that contribution.{% endblock %}
{% block page_content %}
<section>
<div
class=
"bd-callout bd-callout-info"
>
<h1>
A toolkit to facilitate chimeric antigen receptor assembly
</h1>
</div>
<p>
While designing our chimeric antigen receptors (CARs), we noticed that CARs contain an inherently
modular structure: every CAR requires an extracellular domain to recognize a target,
a transmembrane domain to transduce signal into the cell, and an intracellular domain to
induce some reaction by the cell. This realization inspired us to design CAR-TK, a
chimeric antigen receptor toolkit that facilitates modular assembly of CARs.
</p>
</section>
<section>
<div
class=
"bd-callout bd-callout-info"
>
<h1>
An open-source hardware device for continuous rotation of microfuge tubes
</h1>
</div>
<p>
Many protocols—for our project's purposes, protein purification in particular—require constant but gentle mixing of
small quantities of liquids for extended periods of time. Our lab does not have the expensive equipment
capable of this, so we designed and built an end-over-end rotating device and packaged our code
and hardware for future teams and researchers to construct their own end-over-end spinner.
See more on our hardware page!
</p>
</section>
<section>
<div
class=
"bd-callout bd-callout-info"
>
<h1>
An open-source software tool for codon optimization
</h1>
</div>
<p>
After designing DNA sequences, it is crucial to ensure they contain codons easily recognized
by the desired host organism's translation machinery. During our design process, we struggled
with finding easy-to-use and accurate codon optimization software, so we developed our own.
Learn more on our software page!
</p>
</section>
<div
class=
"bd-callout bd-callout-info"
>
<h1>
A toolkit to facilitate chimeric antigen receptor assembly
</h1>
</div>
<p>
While designing our chimeric antigen receptors (CARs), we noticed that CARs contain an inherently
modular structure: every CAR requires an extracellular domain to recognize a target,
a transmembrane domain to transduce signal into the cell, and an intracellular domain to
induce some reaction by the cell. This realization inspired us to design CAR-TK, a
chimeric antigen receptor toolkit that facilitates modular assembly of CARs.
</p>
<div
class=
"bd-callout bd-callout-info"
>
<h1>
An open-source hardware device for continuous rotation of microfuge tubes
</h1>
</div>
<p>
Many protocols—for our project's purposes, protein purification in particular—require constant but gentle mixing of
small quantities of liquids for extended periods of time. Our lab does not have the expensive equipment
capable of this, so we designed and built an end-over-end rotating device and packaged our code
and hardware for future teams and researchers to construct their own end-over-end spinner.
See more on our hardware page!
</p>
<div
class=
"bd-callout bd-callout-info"
>
<h1>
An open-source software tool for codon optimization
</h1>
</div>
<p>
After designing DNA sequences, it is crucial to ensure they contain codons easily recognized
by the desired host organism's translation machinery. During our design process, we struggled
with finding easy-to-use and accurate codon optimization software, so we developed our own.
Learn more on our software page!
</p>
<div
class=
"bd-callout bd-callout-info"
>
<h1>
Improved protocols for HEK293 transfection, hand-cast SDS-PAGE, protein purification, and more.
</h1>
</div>
<p>
</p>
{% endblock %}
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wiki/pages/experiments.html
+
345
−
16
View file @
7d5cbf7c
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