Furthermore, the binding of biomarker with aptamer of Kd of nM levels can usually break the hybridization with Tm of 50 degree celsius. The binding with Kd of micro M can usually break the hybridization with Tm of less than 40 degree celsius.
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As our results show, the resulting aptamer probes were successful and produced satisfactory results that lined up with our mathematical predictions, thus validating our design guidelines.
As our results show, the resulting aptamer probes were successful and produced satisfactory results that lined up with our mathematical predictions, thus validating our design guidelines (please refer to our results page).<br/><br/>
Lastly, we have devised a simple workflow for the detection and quantification of our biomarkers of interest using the Hill equation. For more information, please see our Modeling page.
