diff --git a/wiki/pages/model.html b/wiki/pages/model.html index c970f2c34c764ce2dad6a861545eff5e97aa3aaa..8fc01de54b6d923de6b00b9a78e318f394552adb 100644 --- a/wiki/pages/model.html +++ b/wiki/pages/model.html @@ -516,7 +516,7 @@ \] </p> </div> - <h2>Explanation</h2> + <strong>Explanation</strong> <p> After Ste2 binds with muscone, it interacts with the G protein, causing the exchange of GDP bound to the G protein with GTP in the cytoplasm, releasing Ste4 and Ste18. After Gpa1 catalyzes the @@ -526,7 +526,7 @@ </p> - <h2>Ordinary Differential Equations</h2> + <strong>Ordinary Differential Equations</strong> <div> <p> \[ @@ -544,7 +544,7 @@ \] </p> </div> - <h2>Variables</h2> + <strong>Variables</strong> <table> <thead> <tr> @@ -597,7 +597,7 @@ </tbody> </table> - <h2>Parameters</h2> + <strong>Parameters</strong> <table> <thead> <tr> @@ -647,7 +647,7 @@ </tbody> </table> - <h2>Initial Conditions</h2> + <strong>Initial Conditions</strong> <p> There are \(1{\mu M}\) of Pheromone and \(1{\mu M}\) of inactive G proteins. Known variables are entered, other variables are set to zero, and unknown parameters are defined. After starting the @@ -696,7 +696,7 @@ \end{align*} \] </div> - <h2>Variables</h2> + <strong>Variables</strong> <table> <thead> <tr> @@ -732,7 +732,7 @@ </tbody> </table> - <h2>Parameters</h2> + <strong>Parameters</strong> <table> <thead> <tr> @@ -792,13 +792,45 @@ </tbody> </table> - <h2>Initial conditions</h2> + <strong>Initial conditions</strong> <p>Assume that before signal transduction starts, there are only free Ste5 and just released Ste4Ste18 in the cell, with concentrations both equal to 1, and parameters are assumed. After starting the simulation, reactions occur according to the listed equations, and after a period of time, the concentrations reach equilibrium.</p> <p>TODO: Insert result graph</p> + <h4>Cascading Reactions</h4> + <strong>Reactions</strong> + <div> + \[ + \begin{align*} + Ste5_{off_{Ste11}} + Ste11_{off} & \leftrightarrows Ste5Ste11 \\ + Ste5_{off_{Ste7}} + Ste7_{off} & \leftrightarrows Ste5Ste7 \\ + Ste5_{off_{Fus3}} + Fus3_{off} & \leftrightarrows Ste5Fus3 \\ + \end{align*} + \] + \[ + \begin{align*} + Ste11 & \xrightarrow {Ste20} Ste11_{pS} \\ + Ste11_{pS} & \xrightarrow {Ste20} Ste11_{pSpS} \\ + Ste11_{pSpS} & \xrightarrow {Ste20} Ste11_{pSpSpT} \\ + \end{align*} + \] + \[ + \begin{align*} + Ste7 & \xrightarrow {Ste11_{pS},Ste11_{pSpS},Ste11_{pSpSpT}} Ste7_{pS} \\ + Ste7_{pS} & \xrightarrow {Ste11_{pS},Ste11_{pSpS},Ste11_{pSpSpT}} Ste7_{pSpT}\\ + \end{align*} + \] + \[ + \begin{align*} + Fus3 & \xrightarrow {Ste7_{pS},Ste7_{pSpT}} Fus3_{pY} \\ + Fus3 & \xrightarrow {Ste7_{pS},Ste7_{pSpT}} Fus3_{pT} \\ + Fus3_{pY} & \xrightarrow {Ste7_{pS},Ste7_{pSpT}} Fus3_{pYpT} \\ + Fus3_{pT} & \xrightarrow {Ste7_{pS},Ste7_{pSpT}} Fus3_{pYpT} \\ + \end{align*} + \] + </div> </div> </div>