From 2fe74151c5e1d9b2703aeeea791dcd2d6981da2e Mon Sep 17 00:00:00 2001
From: HouTeng Chan <ht-chen21@mails.tsinghua.edu.cn>
Date: Tue, 24 Sep 2024 07:21:38 +0000
Subject: [PATCH] Update file therapy-system.html
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<h2>Design</h2>
<hr>
<div class="image-container" style="display: flex; flex-direction: column; align-items: center;">
- <img src="https://static.igem.wiki/teams/5187/wiki-therapysystem-fig/fig1.png" alt="ibd_figure" class="shadowed-image" style="width: 60%; max-width: 500px;">
+ <img src="https://static.igem.wiki/teams/5187/wiki-therapysystem-fig/fig1.png" alt="ibd_figure" class="shadowed-image" style="width: 70%; max-width: 550px;">
<p style="text-align: center; font-size: 0.9em; margin-top: 10px;">fig 1 Schematic Representation of our Experimental Design</p>
</div>
<p>We introduced muscone gas molecule receptors derived from mouse olfactory epithelial cells into chassis bioengineered bacteria. The muscone gas molecule receptor is a G protein coupled receptor in eukaryotic cells, and we chose Saccharomyces cerevisiaet as the chassis bioengineering bacterium. By modifying the mating pathway of Saccharomyces cerevisiae, the muscone gas molecule receptor is integrated into the signaling pathway of Saccharomyces cerevisiae. And downstream of the modified mating pathway, lactate dehydrogenase was introduced to alter the anaerobic metabolism pathway of Saccharomyces cerevisiae, synthesizing lactate for the treatment of IBD disease.</p>
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