diff --git a/src/contents/education.tsx b/src/contents/education.tsx index b49c77629461a9cfc3edfdad72a6ddf6a31170b0..090590988804e267aba0386652ea82c72971fe90 100644 --- a/src/contents/education.tsx +++ b/src/contents/education.tsx @@ -70,7 +70,7 @@ export function Education() { // sidenavbar begin <Element name="section1" className="element rounded-border" id='section1'> - <h1>1.overview</h1> + <h1>Overview</h1> <p className="indent">This year, our team has devoted a great deal of effort to the field of education, as we are convinced that the development and popularisation of synthetic biology cannot be achieved without the broad participation and support of the public, which is at the heart of science education.</p> <p className="indent">To this end, we have elaborated a series of promotional materials, taken the initiative to reach out to patient groups, carried out science popularisation activities in schools, and worked to expand our regional influence while actively speaking out on the international stage. At the local level, in particular, we are working hard to reach out to a wider range of people, with a view to creating a far-reaching social impact.</p> <p className="indent">At the same time, we have established a systematic educational mechanism that aims to transform high school students from passive recipients of knowledge to active practitioners at the university level, thus forming a sustainable educational loop.</p> @@ -323,13 +323,13 @@ export function Education() { // sidenavbar begin alt="example" className="image-wide" /> - <figcaption className='caption'>Figure 16 Our Educational Perimeter1</figcaption> + <figcaption className='caption'>Figure 16 Our Educational Perimeter 1</figcaption> <img src="https://static.igem.wiki/teams/5378/9be818cffa6a960902ea3bacf9f6d7f.webp" alt="example" className="image-wide" /> - <figcaption className='caption'>Figure 17 Our Educational Perimeter2</figcaption> + <figcaption className='caption'>Figure 17 Our Educational Perimeter 2</figcaption> </div> <p className="indent"></p> diff --git a/src/contents/engineering.tsx b/src/contents/engineering.tsx index 111349882b09482983a35d489a8db9ffbb10290b..3c6cf20bc73dc1f84c6fa6fb84e2ddf0bd5b6de1 100644 --- a/src/contents/engineering.tsx +++ b/src/contents/engineering.tsx @@ -10,10 +10,10 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink }) => { return ( <div className="side-navbar"> <Nav className="flex-column"> - <Nav.Link as={Link} to="section1" smooth={true} duration={500} className={activeLink === 'section1' ? 'active' : 'notActive'}>Section 1</Nav.Link> - <Nav.Link as={Link} to="section2" smooth={true} duration={500} className={activeLink === 'section2' ? 'active' : 'notActive'}>Section 2</Nav.Link> - <Nav.Link as={Link} to="section3" smooth={true} duration={500} className={activeLink === 'section3' ? 'active' : 'notActive'}>Section 3</Nav.Link> - <Nav.Link as={Link} to="section4" smooth={true} duration={500} className={activeLink === 'section4' ? 'active' : 'notActive'}>Section 4</Nav.Link> + <Nav.Link as={Link} to="section1" smooth={true} duration={500} className={activeLink === 'section1' ? 'active' : 'notActive'}>Overview</Nav.Link> + <Nav.Link as={Link} to="section2" smooth={true} duration={500} className={activeLink === 'section2' ? 'active' : 'notActive'}>Sensing Module Engineering</Nav.Link> + <Nav.Link as={Link} to="section3" smooth={true} duration={500} className={activeLink === 'section3' ? 'active' : 'notActive'}>Metabolic Module Engineering</Nav.Link> + <Nav.Link as={Link} to="section4" smooth={true} duration={500} className={activeLink === 'section4' ? 'active' : 'notActive'}>Reference</Nav.Link> <Nav.Link as={Link} to="section5" smooth={true} duration={500} className={activeLink === 'section5' ? 'active' : 'notActive'}>Section 5</Nav.Link> <Nav.Link as={Link} to="section6" smooth={true} duration={500} className={activeLink === 'section6' ? 'active' : 'notActive'}>Section 6</Nav.Link> <Nav.Link as={Link} to="section7" smooth={true} duration={500} className={activeLink === 'section7' ? 'active' : 'notActive'}>Section 7</Nav.Link> @@ -76,13 +76,19 @@ export function Engineering() { <Element name="section1" className="element rounded-border" id='section1'> - <h2>Section 1</h2> - <p>Content for section 1.</p> + <h2>Overview </h2> + <p>The engineering of the sensing and metabolic modules are two critical steps in the development of Liver-Brain Gardian, our HE prevention probiotics (see the detailed design of Liver-Brain Gardian in the Description and Design pages).</p> + <p>Through multiple design-build-test-learn cycles, we have successfully engineered the PEA-sensing module, which could automatically respond to the increased level of a risk factor, PEA, of HE and initiate downstream expression of the metabolic module. Simultaneously, we have been working on constructing an efficient module that can degrade the pathogenic factor of HE. </p> + <p>During actual operation, we started the first cycle after fully literation research, making the first attempt with theoretical support. Normally problems would arise which urge us to trouble-shoot with experts and dig further into literature to enter the next iteration of engineering cycle. After several iterations, we were able to achieve the original goal in most scenarios and get a comprehensive understanding of our contributions.</p> + <p>In this section on engineering success, we will go through the engineering cycles we went through to develop the PEA-sensing and ammonia-metabolizing EcN. (Figure 1).</p> + <img - src="https://static.igem.wiki/teams/5378/school-badge/yanyintech.webp" + src="https://static.igem.wiki/teams/5378/testengineering/engineering01.webp" alt="example" className="responsive-img" /> + + </Element> <div className="bd-callout bd-callout-info bg-gray"> @@ -91,19 +97,61 @@ export function Engineering() { <Element name="section2" className="element rounded-border" id='section2'> - <h2>Section 2</h2> - <p>Content for section 2.</p> + <h2>Sensing Module Engineering</h2> + <h3>Cycle 1: Determination of a proper Sensor</h3> + <h4>Design</h4> + <p>Since over-accumulated ammonia is one of the pathogenic factors of HE (see our Description page to learn more), we decided to design an ammonia-sensing module first. We envisioned our sensing module to specifically respond to the level of ammonia and could activate the downstream metabolic module to eliminate ammonia. </p> + <p>After literature research, we learned that most bio-sensors are based on transcriptional factor-inducible promoter systems [1]. However, we failed to find such an inducible promoter that can be activated by NH3 with high specificity. Therefore, we had to switch our design to sensing another risk factor of cirrhosis progression that may lead to HE.</p> + <h4>Redesign & Build</h4> + <p>During the next round of literature reading and brain storming, we learned that the level of bile acid decreases in cirrhosis patients and it was verified in some clinical studies[2-3], so we endeavored to seek systems that could respond to bile acids. Under the generous help and suggestions of Professor Zhu Bo (find more in our integrated human practice page), we found MartÃnez et al in 2019 developed bile acid inducible promoters in Lactobacillus strains[4]. </p> + <p>However, the level of bile acid is negatively related to the severity of cirrhosis, so we tried to utilize the "NOT" logic gate by introducing Cl/Plam genetic circuit. Plam is a potent promoter found in the lambda bacteriophage, while Cl is an inhibitory protein that can bind to the Plam promoter, thereby repressing downstream gene expression[5].</p> + <p>Next, we re-designed the sensing module as shown in Figure 2. The normal level of bile acid can activate the expression of pchA downstream of the inducible bile acid promoter, releasing transcriptional factor pchA to activate PLEE1 and express CL, which can inhibit Plam to express metabolic module. In contrast, when bile acid decreases in cirrhosis patients who are likely to develop HE, the inhibitory effect can be eliminated and thus initiate the expression of metabolic module to work.</p> + <h4>Test</h4> + <p>To ensure the feasibility of our design before construction of plasmids, we did broad HP investigations, literature reviews, group discussions and expert outreach. Professor Zhu Bo suggested us to interview experts in the field of liver diseases, especially in HE. Our HP group reached Professor He Xiaolong, who has been studying the mechanism of gut microbiota and its metabolites in the development of HE. He pointed out that although our design seemed very interesting, bile acids are not specific enough as a biomarker for HE. </p> + <p>Coincidentally, his team currently found a new type of gut microbiota-derived metabolite, PEA, and verified its specificity and sensitivity in animal models and patients (Figure 3, unpublished work in submission). He generously reported this work to us and showed great interest in the concept of engineering probiotics to prevent HE from progressing. Therefore, we invited him to our team as secondary PI and moved our attention to PEA as the sensor.</p> + <h4>Learn</h4> + <p>We ultimately chose to use PEA as the sensing marker for our engineered bacteria. </p> + <h3>Cycle 2: Construction of the Sensing Module</h3> + <h4>Design & Build</h4> + <p>To specifically respond to PEA, we designed a TynA-FeaR-PTynA inducible system. In Escherichia coli, TynA is a monoamine oxidase that can oxidize aromatic amines such as PEA to the corresponding aldehyde, PAG. FeaR is a transcription factor, which was shown to activate PtynA in the presence of aldehydes. Therefore, we designed a plasmid that constantly express TynA and FeaR and another plasmid with the inducibel promoter PTynA and downstream gene to be activated. </p> + <p>However, TynA can oxidize various kinds of aromatic amines and lack specificity to PEA. Through literature reading, we learned that Rottinghaus et al found the mutant TynA-G494S and FeaR-A81L showed a more specific response to PEA and PAG[6]. Therefore, we constructed the plasmid Pcon-FeaR+Pcon-TynA with the two mutants and a plasmid with inducible promoter PTynA and a reporter gene GFP (Figure 4).</p> + <h4>Test</h4> + <p>We planned to co-transformed EcN with two plasmids via electroporation (Protocol-1). However, colony PCR suggested we only transformed successfully with plasmid Pcon-feaR-PcontynA and failed in transforming plasmid PTynA-GFP. We tried several times but all came with negative results (Figure 5).</p> + <h4>Learn</h4> + <p>Our experiment group members analyzed reasons carefully and searched for chemical transformation protocol in EcN (Protocol-2). Fortunately, colony PCR showed successful construction of our engineered EcN (Figure 6) and it was verified by DNA sequencing.</p> + <h3>Cycle 3: Optimizing inducing condition of the Sensing Module</h3> + <h4>Design & Build</h4> + <p>After transformation of two plasmids in EcN, we tried to validate the PEA-sensing GFP reporting system with different concentrations of PEA (0, 5, 25, 50 and 100 ng/ml) and explored the optimized inducing concentration of PEA.</p> + <h4>Test</h4> + <p>After co-culture with different concentraions of PEA for different time (0,4,8,12 and 24h), the fluorescence was measured on microplate reader by excitation at 410 nm and detection of emission at 500 nm. OD600 (absorbance of 600nm) was also measured on microplate reader for normalization.</p> + <h4>Learn</h4> + <p>Results showed a significant increase in fluorescent intensity along with the increased level of PEA concentration. 100 ng/ml PEA presented the best capability of induction, and showed significant difference compared with other concentrations of PEA starting from 12 hours.</p> <img src="https://static.igem.wiki/teams/5378/school-badge/yanyintech.webp" alt="example" className="responsive-img" /> + <p>Therefore, the design of sensing module, which detects the rising level of HE risk factor PEA and induces the expression of gene downstream, is feasible. The opmized concentration of PEA can be set at 100 ng/ml. </p> </Element> <Element name="section3" className="element rounded-border" id='section3'> - <h2>Section 3</h2> - <p>Content for section 3.</p> + <h2>Metabolic Module Engineering</h2> + <h3>Cycle 1: Determination of a proper pathogenic factor</h3> + <h4>Design</h4> + <p>1</p> + <h4>Build & Test</h4> + <p>2</p> + <h4>Learn</h4> + <p>3</p> + <h3>Cycle 2: </h3> + <h4>Design</h4> + <p>1</p> + <h4>Build & Test</h4> + <p>2</p> + <h4>Learn</h4> + <p>3</p> + <p>4</p> <div className="rounded-border"> <h4 className="center-text">我是大帅B</h4> <p className="indent">las ijffs aiskfd fskj iiwls asd.aass ffas awssd awus iisal fask.aisisad ksjdfkaf iwjasifjakdshf wijdfalksjf wiksjkfjksalhf, gsahfjhgejkfh uhaejkfh sjdihgfuqiw jh sjiafhjsaj fh asd.</p> diff --git a/src/contents/experiments.tsx b/src/contents/experiments.tsx index ab9d5a783cec8d0e815ecb2656a9ed2818c434b2..ae2df4467dea56b499726e1b1f5a3f574a2ca5c4 100644 --- a/src/contents/experiments.tsx +++ b/src/contents/experiments.tsx @@ -19,7 +19,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section1' ? 'active' : 'notActive'} onClick={() => onLinkClick('section1')} > - Section 1 + LB medium preparation </Nav.Link> <Nav.Link as={Link} @@ -29,7 +29,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section2' ? 'active' : 'notActive'} onClick={() => onLinkClick('section2')} > - Section 2 + Double Enzyme DNA Digestion& Agarose Gel Electrophoresis </Nav.Link> {/* æ·»åŠ æ›´å¤šå¯¼èˆªé“¾æŽ¥ */} @@ -42,7 +42,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section3' ? 'active' : 'notActive'} onClick={() => onLinkClick('section3')} > - Section 3 + Agarose Gel Electrophoresis </Nav.Link> <Nav.Link @@ -53,7 +53,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section4' ? 'active' : 'notActive'} onClick={() => onLinkClick('section4')} > - Section 4 + Infusion </Nav.Link> <Nav.Link @@ -64,7 +64,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section5' ? 'active' : 'notActive'} onClick={() => onLinkClick('section5')} > - Section 5 + Colony PCR </Nav.Link> <Nav.Link @@ -75,7 +75,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section6' ? 'active' : 'notActive'} onClick={() => onLinkClick('section6')} > - Section 6 + Plasmid conservation </Nav.Link> <Nav.Link @@ -86,7 +86,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section7' ? 'active' : 'notActive'} onClick={() => onLinkClick('section7')} > - Section 7 + Plasmid Extraction </Nav.Link> <Nav.Link @@ -97,7 +97,7 @@ const SideNavbar: React.FC<SideNavbarProps> = ({ activeLink, onLinkClick }) => { className={activeLink === 'section8' ? 'active' : 'notActive'} onClick={() => onLinkClick('section8')} > - Section 8 + Transformation </Nav.Link> </Nav> </div> @@ -159,16 +159,16 @@ export function Experiments() { <div className="col-10"> <Element - name="section1" + name="section 1" className="element rounded-border" - id='section1' + id='section 1' onMouseEnter={() => handleMouseEnter('section1')} style={{ display: visibleSection === 'section1' ? 'block' : 'none' }} > - <h2>Section 2</h2> + <h2>LB medium preparation</h2> <p>Content for section 2.</p> <div className="rounded-border"> - <h4 className="center-text">Section 2</h4> + <h4 className="center-text">LB medium preparation</h4> <p className="indent">las ijffs aiskfd fskj iiwls asd.aass ffas awssd awus iisal fask.aisisad ksjdfkaf iwjasifjakdshf wijdfalksjf wiksjkfjksalhf, gsahfjhgejkfh uhaejkfh sjdihgfuqiw jh sjiafhjsaj fh asd.</p> <p className="indent">las ijffs aiskfd fskj iiwls asd.aass ffas awssd awus iisal fask.aisisad ksjdfkaf iwjasifjakdshf wijdfalksjf wiksjkfjksalhf, gsahfjhgejkfh uhaejkfh sjdihgfuqiw jh sjiafhjsaj fh asd.</p> </div> @@ -182,10 +182,10 @@ export function Experiments() { onMouseEnter={() => handleMouseEnter('section2')} style={{ display: visibleSection === 'section2' ? 'block' : 'none' }} > - <h2>Section 2</h2> + <h2>LB medium preparation</h2> <p>Content for section 2.</p> <div className="rounded-border"> - <h4 className="center-text">Section 2</h4> + <h4 className="center-text">LB medium preparation</h4> <p className="indent">las ijffs aiskfd fskj iiwls asd.aass ffas awssd awus iisal fask.aisisad ksjdfkaf iwjasifjakdshf wijdfalksjf wiksjkfjksalhf, gsahfjhgejkfh uhaejkfh sjdihgfuqiw jh sjiafhjsaj fh asd.</p> <p className="indent">las ijffs aiskfd fskj iiwls asd.aass ffas awssd awus iisal fask.aisisad ksjdfkaf iwjasifjakdshf wijdfalksjf wiksjkfjksalhf, gsahfjhgejkfh uhaejkfh sjdihgfuqiw jh sjiafhjsaj fh asd.</p> </div> diff --git a/src/contents/inclusivity.tsx b/src/contents/inclusivity.tsx index 946eb53d10999f8f1aa8b6b97b697acbc36ec32e..ad28040963b3392d423ccb470820a53955b55a7c 100644 --- a/src/contents/inclusivity.tsx +++ b/src/contents/inclusivity.tsx @@ -71,10 +71,10 @@ export function Inclusivity() { <Element name="section3" className="element rounded-border" id='section3'> <h2>Overview</h2> - <p>"We are all connected in the great web of existence." — Chief Seattle</p> + <p>"We are all connected in the great web of existence. — Chief Seattle</p> <div className="rounded-border"> <h4 className="center-text">To see</h4> - <p className="indent">Through iGEM, we recognize the importance of diversity and inclusivity in the scientific community.Our team is committed to the inclusion of people from diverse backgrounds in scientific research, particularly in the areas of educational equity and social inclusion in urban and rural areas. Through a series of concrete activities, we help people of different identities and backgrounds to learn about science, in particular the importance and applications of hepatic encephalopathy and synthetic biology. Our aim is to enable everyone to do their part to improve health and promote scientific progress, and to stimulate interest in scientific research, wherever they come from.</p> + <p className="indent">Through iGEM, we recognize the importance of diversity and inclusivity in the scientific community. Our team is committed to the inclusion of people from diverse backgrounds in scientific research, particularly in the areas of educational equity and social inclusion in urban and rural areas. Through a series of concrete activities, we help people of different identities and backgrounds to learn about science, in particular the importance and applications of hepatic encephalopathy and synthetic biology. Our aim is to enable everyone to do their part to improve health and promote scientific progress, and to stimulate interest in scientific research, wherever they come from.</p> </div> <div className='image-container'> <img @@ -186,7 +186,7 @@ export function Inclusivity() { <Element name="section5" className="element rounded-border" id='section5'> <h2>Assistance Engineering</h2> - <p>To Address Regional Development Imbalances and Unequal Resource Distribution (Such as Educational Opportunities, Service Access, and Resource Acquisition),Southern Medical University (SMU) has formed a support team to assist Guangdong Medical University (GMU) in various ways. Through this mutually beneficial partnership, SMU and GMU demonstrate how support and collaboration can lead to significant progress for both institutions. Notably, our team consists of students from both universities, which is a vivid representation of this cooperative relationship. Through an interview with Professor Li Ling, the leader of the SMU support team and mentor of the SMU&GDMU iGEM team, we learned that the goals of this support initiative are:</p> + <p>To Address Regional Development Imbalances and Unequal Resource Distribution (Such as Educational Opportunities, Service Access, and Resource Acquisition), Southern Medical University (SMU) has formed a support team to assist Guangdong Medical University (GDMU) in various ways. Through this mutually beneficial partnership, SMU and GDMU demonstrate how support and collaboration can lead to significant progress for both institutions. Notably, our team consists of students from both universities, which is a vivid representation of this cooperative relationship. Through an interview with Professor Li Ling, the leader of the SMU support team and mentor of the SMU&GDMU iGEM team, we learned that the goals of this support initiative are:</p> <div className='image-container'> <img src="https://static.igem.wiki/teams/5378/award-inclusivity/7.webp" @@ -197,23 +197,23 @@ export function Inclusivity() { </div> <div className="rounded-border"> <h4 className="center-text">(1) Achieving Interdisciplinary Integration:</h4> - <p className="indent">By forming research teams in foundational medical sciences, clinical medicine, and other fields, we aim to promote interdisciplinary integration, reflecting the interdisciplinary spirit of iGEM. For example, SMU and GMU can jointly conduct a research project on genetic disease gene therapy, combining SMU's expertise in genetics with GMU's experience in clinical applications to form complementary research strengths.</p> + <p className="indent">By forming research teams in foundational medical sciences, clinical medicine, and other fields, we aim to promote interdisciplinary integration, reflecting the interdisciplinary spirit of iGEM. For example, SMU and GDMU can jointly conduct a research project on genetic disease gene therapy, combining SMU's expertise in genetics with GDMU's experience in clinical applications to form complementary research strengths.</p> </div> <div className="rounded-border"> - <h4 className="center-text">(2)Building a 'Collaborative Talent Cultivation' System:</h4> - <p className="indent">Through joint talent cultivation programs, such as integrated undergraduate-master’s degree programs and exchange student initiatives, we provide students with broader learning platforms, emphasizing iGEM's commitment to talent development. Additionally, we implement summer internship programs, allowing students to conduct research internships in the laboratories of the partner university, enhancing practical experience and research capabilities.</p> + <h4 className="center-text">(2)Building a 'Collaborative Talent Cultivation' System:</h4> + <p className="indent">Through joint talent cultivation programs, such as integrated undergraduate-master' s degree programs and exchange student initiatives, we provide students with broader learning platforms, emphasizing iGEM's commitment to talent development. Additionally, we implement summer internship programs, allowing students to conduct research internships in the laboratories of the partner university, enhancing practical experience and research capabilities.</p> </div> <div className="rounded-border"> - <h4 className="center-text">(3)Research Collaboration:</h4> + <h4 className="center-text">(3)Research Collaboration:</h4> <p className="indent">The support team facilitates the establishment of shared laboratories and research centers, promoting the sharing of research resources and enhancing collaboration between researchers in synthetic biology and related fields, reflecting iGEM's ethos of shared research. Furthermore, the support team regularly organizes joint research projects, inviting researchers from both sides to apply for national and international research grants, driving high-level research outcomes.</p> </div> <div className="rounded-border"> - <h4 className="center-text">(4)Achieving Equal Access to Educational Resources:</h4> + <h4 className="center-text">(4)Achieving Equal Access to Educational Resources:</h4> <p className="indent">The support team promotes the opening of course resources and online education platforms, benefiting more students from both universities, reflecting iGEM's principle of equitable access to educational resources. Additionally, student exchange programs are established, and regular academic symposiums are held to promote interaction and cooperation among students, eliminating barriers caused by unequal distribution of educational resources.</p> - <p className="indent">Through this support process, both institutions ultimately benefit and achieve a win-win situation. SMU is not only supporting GMU but also achieving its own growth and progress. For example, by jointly undertaking national-level research projects, both research teams can showcase their achievements on high-level platforms, enhancing research capabilities and innovation. Simultaneously, shared resources and best practices elevate the overall quality of education. Moreover, this support initiative helps both institutions build a broader academic and professional network, increasing opportunities for future collaborations.</p> + <p className="indent">Through this support process, both institutions ultimately benefit and achieve a win-win situation. SMU is not only supporting GDMU but also achieving its own growth and progress. For example, by jointly undertaking national-level research projects, both research teams can showcase their achievements on high-level platforms, enhancing research capabilities and innovation. Simultaneously, shared resources and best practices elevate the overall quality of education. Moreover, this support initiative helps both institutions build a broader academic and professional network, increasing opportunities for future collaborations.</p> </div> </Element> @@ -222,17 +222,17 @@ export function Inclusivity() { <h2>From evidence to narrative: humanistic care and inclusive practice in medicine</h2> <p>Against the backdrop of rapidly evolving medical technology, we recognise that relying on data and standardised treatments alone cannot fully meet the needs of patients. For this reason, we have turned to narrative medicine. Through an in-depth conversation with Professor Xiaolin Yang from the Centre for Narrative Medicine at Southern Medical University, we have learned how to incorporate more humanistic care into medical practice and communicate with doctors to apply it in their clinical practice. Narrative medicine emphasises an equal dialogue between doctors and patients, understanding patients' unique experiences by listening to their stories and engaging them to provide a more personalised treatment plan.</p> <div className="rounded-border"> - <h4 className="left-text">(1)Narrative Intervention and Prescription:</h4> + <h4 className="left-text">(1)Narrative Intervention and Prescription:</h4> <p className="indent">Doctors actively listen to the patient's personal story and use it as part of the treatment plan, while providing emotional support and psychological relief to enhance treatment outcomes.</p> - <h4 className="left-text">(2)Establishment of a support network:</h4> + <h4 className="left-text">(2)Establishment of a support network:</h4> <p className="indent">Create a community of patients, family members and healthcare professionals to facilitate experience sharing and resource exchange, and enhance mutual psychological support.</p> - <h4 className="left-text">(3)Diversified participation:</h4> + <h4 className="left-text">(3)Diversified participation:</h4> <p className="indent">Provide scholarships and internship opportunities for students from different backgrounds, especially supporting members of underrepresented groups such as women and ethnic minorities.</p> - <h4 className="left-text">(4)Elimination of social prejudice:</h4> + <h4 className="left-text">(4)Elimination of social prejudice:</h4> <p className="indent">Increase public awareness of hepatic encephalopathy through media and community activities to reduce misunderstanding and discrimination.</p> - <h4 className="left-text">(5)Patient participation mechanisms:</h4> + <h4 className="left-text">(5)Patient participation mechanisms:</h4> <p className="indent">Encourage patients to participate in their own treatment decisions, and provide channels for feedback so that patients' voices can be heard.</p> - <h4 className="left-text">(6)Interdisciplinary co-operation:</h4> + <h4 className="left-text">(6)Interdisciplinary co-operation:</h4> <p className="indent">Collaborate with experts from multiple fields to form a multidisciplinary team to provide comprehensive services and support. This philosophy holds true for iGEM, synthetic biology, and the broader sciences as well. We believe that anyone should have the opportunity to have a voice and contribute to these communities.</p> </div> <div className='image-container'> @@ -307,7 +307,7 @@ export function Inclusivity() { <h4 className="center-text">Collaboration</h4> <p className="indent">Our team collaborates with the Hepatology Center at Nanfang Hospital and the Microecology Treatment Center at Zhujiang Hospital. Under their guidance, we collected serum samples from patients with cirrhosis before undergoing TIPS surgery and performed metabolomics testing. We also followed up with the patients for three months to record the occurrence of HE.</p> <p className="indent">Our team participated in the South China Exchange Conference, where we shared our project progress and experiences with Shenzhen University, Southern University of Science and Technology, and others.</p> - <p className="indent">Our team was invited to participate in the China Regional Exchange Conference (CCIC), where we engaged in in-depth discussions with other teams regarding project optimization and improvements. This enhanced our collaborative abilities and promoted the development of each team's projects.</p> + <p className="indent">Our team was invited to participate in the 11th China Regional iGEMer Exchange Conference (CCIC), where we engaged in in-depth discussions with other teams regarding project optimization and improvements. This enhanced our collaborative abilities and promoted the development of each team's projects.</p> <div className='image-container'> <img src="https://static.igem.wiki/teams/5378/award-inclusivity/12.webp"