From 14dbb814e6ca748b3833aef69ff6532354e9d25c Mon Sep 17 00:00:00 2001 From: Mengying Zhao <28220326@njnu.edu.cn> Date: Mon, 30 Sep 2024 12:24:24 +0000 Subject: [PATCH] Update file description.html --- wiki/pages/description.html | 14 +++++++------- 1 file changed, 7 insertions(+), 7 deletions(-) diff --git a/wiki/pages/description.html b/wiki/pages/description.html index dcc242e..a6faa81 100644 --- a/wiki/pages/description.html +++ b/wiki/pages/description.html @@ -28,17 +28,17 @@ <div class="pagebody"> <div class="pagenav"> <div onclick="goTo(document.getElementById('one'))"><span id="subtitle1" - style="color: green;">Introduction</span></div> + style="color: green;"><strong>Introduction</strong></span></div> <div onclick="goTo(document.getElementById('two'))"><span id="subtitle2" - style="color: green;">What Is the Problem?</span></div> + style="color: green;"><strong>What Is the Problem?</strong></span></div> <div onclick="goTo(document.getElementById('three'))"><span id="subtitle3" - style="color: green;">Current Solutions</span></div> + style="color: green;"><strong>Current Solutions</strong></span></div> <div onclick="goTo(document.getElementById('four'))"><span id="subtitle4" - style="color: green;">Policy Support</span></div> + style="color: green;"><strong>Policy Support</strong></span></div> <div onclick="goTo(document.getElementById('five'))"><span id="subtitle5" - style="color: green;">The Project</span></div> + style="color: green;"><strong>The Project</strong></span></div> <div onclick="goTo(document.getElementById('six'))"><span id="subtitle6" - style="color: green;">Reference</span></div> + style="color: green;"><strong>Reference</strong></span></div> </div> <div class="pagecontent"> <!-- 1 --> @@ -75,7 +75,7 @@ <img src="https://static.igem.wiki/teams/5303/description/9-1.png" alt=""> </div> <span class="figure-font">Fig.4 5-ALA structural diagram</span> - <p>At present, 5-ALA is mainly synthesized by chemical synthesis and microbial fermentation. The study of chemical synthesis began in the 50s of the 20th century, and was most active in the 90s. The researchers synthesized 5-ALA [9] using raw materials such as hippuric acid, succinic acid, tetrahydrofurfuramine, and levulinic acid. However, the chemical synthesis method has the disadvantages of high price, difficult to obtain, high toxicity, low production yield and harsh reaction conditions, and the synthetic products contain impurities that are difficult to determine, which may cause potential harm to agricultural and forestry [8]. <strong>In this project, <i>E. coli</i> was used as the chassis to screen strains that can produce stable and high yields of 5-ALA through enzyme modification, CRISPR transposition, and microfluidic high-throughput screening</strong>. Finally, the efficient and sustainable production of 5-ALA will be realized, thereby reducing the cost of biopesticides and contributing to the alleviation of the global food crisis. </p > + <p>At present, 5-ALA is mainly synthesized by chemical synthesis and microbial fermentation. The study of chemical synthesis began in the 50s of the 20th century, and was most active in the 90s. The researchers synthesized 5-ALA [9] using raw materials such as hippuric acid, succinic acid, tetrahydrofurfuramine, and levulinic acid. However, the chemical synthesis method has the disadvantages of high price, difficult to obtain, high toxicity, low production yield and harsh reaction conditions, and the synthetic products contain impurities that are difficult to determine, which may cause potential harm to agricultural and forestry [8]. <strong>In this project, <i>E. coli</i> was used as the chassis to screen strains that can produce stable and high yields of 5-ALA through enzyme modification, CRISPR-associated transposons (CASTs) system, and microfluidic high-throughput screening</strong>. Finally, the efficient and sustainable production of 5-ALA will be realized, thereby reducing the cost of biopesticides and contributing to the alleviation of the global food crisis. </p > </div> <div class="h" id="four"> <div class="h1">Policy Support</div> -- GitLab