diff --git a/wiki/pages/attributions.html b/wiki/pages/attributions.html index b5bec8ffae21be2ab0227d805425f300a914ad13..c5f6d3305975eea37001aa936052164f9093e497 100644 --- a/wiki/pages/attributions.html +++ b/wiki/pages/attributions.html @@ -10,7 +10,8 @@ text-align: justify; } </style> -<div class="col-8"> +<div class="row justify-content-center"> + <div class="col-lg-10"> <h1 class="text-center padding display-4"> From Genesis, Till Now </h1> @@ -129,7 +130,7 @@ </p> <hr> <div style="height: 5rem;"></div> -</div> +</div></div> <!-- <div class="row mt-4"> <div class="col"> <div> diff --git a/wiki/pages/contribution.html b/wiki/pages/contribution.html index 047b5832f40547bed35204ca9775380c4c60d581..ec3ca8706e988ebb704d8a9dc71cb4cf3ad49061 100644 --- a/wiki/pages/contribution.html +++ b/wiki/pages/contribution.html @@ -5,16 +5,149 @@ {% block page_content %} -<div class="row mt-4"> - <div class="col"> - <div class="bd-callout bd-callout-info"> - <h4>Bronze Medal Criterion #4</h4> - <p>Make a useful contribution for future iGEM teams. Use this page to document that contribution.</p> - <p>If you are making a contribution by adding information to an existing Part or creating a new Part, you must document your contribution on the Part's Main Page on the <a href="https://parts.igem.org/Main_Page">Registry</a> for your team to be eligible for this criteria. You can use this page to link to that part and include additional information about your contribution.</p> - <hr> - <p>Please see the <a href="https://competition.igem.org/judging/medals">2024 Medals Page</a> for more information.</p> - </div> - </div> -</div> +<style> + body { + font-family: Arial, sans-serif; + margin: 20px; + text-align: center; + } + table { + width: 100%; + max-width: 1000px; + margin: 0 auto; + border-collapse: collapse; + } + table, th, td { + border: 1px solid black; + } + th, td { + padding: 10px; + text-align: justify; + vertical-align: top; + } + th { + background-color: #f2f2f2; + } + @media (max-width: 600px) { + th, td { + font-size: 14px; + } + } + + img { + max-height: 500rem; + max-width: auto; + display: block; + margin-left: auto; + margin-right: auto;} + + figure { + display: table; + padding: 5px; + background-color: #fff; + font-size: .875em; + +} + +figure img { + display: block; + max-width: 100%; +} + +figcaption { + display: table-caption; + caption-side: bottom; + background: #fff; + padding: 0 5px 5px;} + +</style> + + <h1>Our Contributions to the iGEM Community</h1> + <div style="height: 4rem;"></div> + <p class="padding" style="text-align: justify;"> + The real aim of the project was to set a precedent in the approach of targeting and clearing misfolded proteins using Aptamers. We used Tau as a model and phosphorylation as the label. We have a few registry parts which may be useful to future teams working with Tau or implementing any therapeutics against Tauopathies. + </p> + <table class="padding"> + <tr> + <th>Registry Parts</th> + <th>Designers</th> + <th>Short Description</th> + <th>Type</th> + </tr> + <tr> + <td>BBa_K5170000</td> + <td>Subhanan Banerjee, Suvam Saswat Das, Avani, Anurag Sarkar, Parth Kumar</td> + <td>A Novel PROTAC using BBa_K5170004</td> + <td>Conjugate</td> + </tr> + <tr> + <td>BBa_K5170001</td> + <td>Subhanan Banerjee, Suvam Saswat Das, Avani, Anurag Sarkar, Parth Kumar</td> + <td>A Novel PROTAC using BBa_K5170002</td> + <td>Conjugate</td> + </tr> + <tr> + <td>BBa_K5170002</td> + <td>I-Ting Teng, Xiaowei Li, Hamad Ahmad Yadikar, Zhihui Yang, Long Li, Yifan Lyu, Xiaoshu Pan, Kevin K. Wang, Weihong Tan</td> + <td>DNA Aptamer against 231pTau</td> + <td>DNA</td> + </tr> + <tr> + <td>BBa_K5170003</td> + <td>I-Ting Teng, Xiaowei Li, Hamad Ahmad Yadikar, Zhihui Yang, Long Li, Yifan Lyu, Xiaoshu Pan, Kevin K. Wang, Weihong Tan</td> + <td>DNA Aptamer against 231pTau</td> + <td>DNA</td> + </tr> + <tr> + <td>BBa_K5170004</td> + <td>I-Ting Teng, Xiaowei Li, Hamad Ahmad Yadikar, Zhihui Yang, Long Li, Yifan Lyu, Xiaoshu Pan, Kevin K. Wang, Weihong Tan</td> + <td>DNA Aptamer against 231pTau</td> + <td>DNA</td> + </tr> + <tr> + <td>BBa_K5170005</td> + <td>Subhanan Banerjee, Suvam Saswat Das, Avani, Anurag Sarkar, Parth Kumar</td> + <td>A Novel PROTAC using BBa_K5170003</td> + <td>Conjugate</td> + </tr> + <tr> + <td>BBa_K5170006</td> + <td>Suvam Saswat Das</td> + <td>Phosphomimetic Tau compatible with pET29b vector</td> + <td>Protein Domain</td> + </tr> + </table> +<div style="height: 5rem;"></div> + +<div class="row justify-content-center"> + <div class="col-lg-9"> +<figure> + <img src="https://static.igem.wiki/teams/5170/contribution/1.webp" alt="alt" style="max-height: auto; + max-width: 75%; + display: block; + margin-left: auto; + margin-right: auto;"> + <figcaption>The modified ligand linked base can joined in the 3' terminal of an Aptamer. This is a tool that can convert the activity of the aptamer into that of a PROTAC upon incorporation by Terminal Deoxynucleotidyl Transferase.</figcaption> +</figure> +</div></div> +<div style="height: 5rem;"></div> + +<div class="row justify-content-center"> + <div class="col-lg-9"> +<figure> + <img src="https://static.igem.wiki/teams/5170/contribution/2.webp" alt="alt"> + <figcaption>Illustration of the modified ligand linked base bound with the 3’ of the Aptamer (A-T-G-T-modified C)</figcaption> +</figure> +</div></div> + +<div class="row justify-content-center"> + <div class="col-lg-9"> +<div style="height: 5rem;"></div> +<figure> + <img src="https://static.igem.wiki/teams/5170/contribution/3.webp" alt="alt"> + <figcaption>BBa_K5170006 shown in pET29b vector, highlighted in blue. It can be expressed in E. coli BL21 via this vehicle.</figcaption> +</figure> +</div></div> +<div style="height: 10rem;"></div> {% endblock %} diff --git a/wiki/pages/partcollection.html b/wiki/pages/partcollection.html index 40d9adb6d5e2571a35c43df70ae11a607b232ad6..29a73c366f781bdbc9edbf230b31f42e61919bfe 100644 --- a/wiki/pages/partcollection.html +++ b/wiki/pages/partcollection.html @@ -31,4 +31,20 @@ </div> </div> --> +<div class="row justify-content-center"> + <div class="col-lg-10"> + <h2 class="padding"> The following parts were collected as a part of our iGEM Journey:</h2> + <div style="height: 3rem;"></div> + <ol> + <li><a href="https://parts.igem.org/Part:BBa_K5170000">https://parts.igem.org/Part:BBa_K5170000</a></li> + <li><a href="https://parts.igem.org/Part:BBa_K5170001">https://parts.igem.org/Part:BBa_K5170001</a></li> + <li><a href="https://parts.igem.org/Part:BBa_K5170002">https://parts.igem.org/Part:BBa_K5170002</a></li> + <li><a href="https://parts.igem.org/Part:BBa_K5170003">https://parts.igem.org/Part:BBa_K5170003</a></li> + <li><a href="https://parts.igem.org/Part:BBa_K5170004">https://parts.igem.org/Part:BBa_K5170004</a></li> + <li><a href="https://parts.igem.org/Part:BBa_K5170005">https://parts.igem.org/Part:BBa_K5170005</a></li> + <li><a href="https://parts.igem.org/Part:BBa_K5170006">https://parts.igem.org/Part:BBa_K5170006</a></li> + </ol> + </div> +</div> +<div style="height: 10rem;"></div> {% endblock %}