From aa056aad12454b34e1990aa775fa961b2336e2fe Mon Sep 17 00:00:00 2001
From: Angela Wang <angeluhwang@gmail.com>
Date: Wed, 2 Oct 2024 12:58:54 +0000
Subject: [PATCH] Update file description.html
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1 file changed, 5 insertions(+), 7 deletions(-)
diff --git a/wiki/pages/description.html b/wiki/pages/description.html
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Research has shown that G9a activity is responsible for regulating the genes that influence the production and release of dopamine; thus, the G9a enzyme impacts how the brain responds to addictive substances. In a 2018 study of male rats, scientists examined how reducing G9a expression in the nucleus accumbens, the brain region associated with reward responses, impacts addiction and anxiety-related behaviors. They found that reducing the levels of G9a in rats’ brains decreased their desire to consume cocaine, suggesting that G9a plays a crucial role in addictive behaviors. On top of that, reducing G9a also reduced the likelihood of the rats seeking cocaine again after a period of abstinence, reducing the chance for relapse. Given that a major challenge with current addiction treatment is the risk for relapse, this research suggests that G9a research is a promising way to help diminish that risk and enhance treatments. The decreased addictive behavior caused by G9a knockdown also led to reduced anxiety-like behaviors. Anxiety and addiction often occur concurrently in individuals, making it necessary to design treatments that can target both behaviors. Understanding the influence of G9a in both anxiety and addiction raises the possibility of developing treatments that can focus on both disorders (Anderson 2019).
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- <small><i>The graph above (from the Human Protein Atlas) visualizes the EHMT2 RNA found to be in parts of the brain significantly more than other bodily structures. </i></small>
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+ <img src="https://static.igem.wiki/teams/5535/projectdescription1.webp" alt="p-d-img1" class="image">
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<small><i>The graph above (from the Human Protein Atlas) visualizes the EHMT2 RNA found to be in parts of the brain significantly more than other bodily structures.</i></small>
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<h2 style="font-family: 'soulmeh', sans-serif;">References:</h2>
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NIDA. "Most reported substance use among adolescents held steady in 2022." National Institute on Drug Abuse, 15 Dec. 2022,
https://nida.nih.gov/news-events/news-releases/2022/12/most-reported-substance-use-among-adolescents-held-steady-in-2022 <br>
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