From 5a0c76215c4ef4ed99e9341a91b588d459dca3d6 Mon Sep 17 00:00:00 2001
From: Angela Wang <angeluhwang@gmail.com>
Date: Wed, 2 Oct 2024 11:50:08 +0000
Subject: [PATCH] Update file home.html
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<div class="carousel-item top-left">Los Angeles County is notorious for its rising rates of substance abuse. 7.6% of Los Angeles County residents aged 12 and above live with a substance use disorder, meaning over 760,000 people are affected within our communities, districts, and schools.</div>
<div class="carousel-item top-right">Drugs produce an intense feeling of euphoria, causing an unhealthy amount of dopamine production and release in the brain. Our human brains are wired to remember pleasurable activities to increase the chances of its recurrence. The dopaminergic pathway is responsible for the human system’s pleasure circulation.</div>
<div class="carousel-item bottom-left">Research has shown that G9a activity is responsible for regulating the genes that influence the production and release of dopamine. They found that reducing the levels of G9a in rats’ brains decreased their desire to consume cocaine, suggesting that G9a plays a crucial role in addictive behaviors.</div>
- <div class="carousel-item bottom-right" style="font-size: 40px">Next -></div>
+ <div class="carousel-item bottom-right" style="font-size: 40px"> -></div>
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<div class="carousel-slide">
- <div class="carousel-item top-left" style="text-align: center"><b style="font-size: 50px">CALIMOD<b><br>
-To introduce this overexpression of G9a, we designed a three-component system to address all aspects of this problem more inclusively and comprehensively:</div>
+ <div class="carousel-item top-left" style="text-align: center">CALIMOD<br>
+ To introduce this overexpression of G9a, we designed a three-component system to address all aspects of this problem more inclusively and comprehensively:</div>
<div class="carousel-item top-right"><b>1.Plasmid Creation:</b> We will construct and validate a plasmid with a CMV promoter and puromycin resistance gene in DH5α E. coli.</div>
<div class="carousel-item bottom-left"><b>2. siRNA Transfection:</b> We will design and test small interfering RNA (siRNA) to lower G9a expression in HEK293-T cells.</div>
<div class="carousel-item bottom-right"><b>3.Lipid Nanoparticle Targeting:</b> We will develop lipid nanoparticles to deliver siRNA specifically to the nucleus accumbens shell.</div>
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