diff --git a/src/data/hptimelinedata.tsx b/src/data/hptimelinedata.tsx index ab43a725001dbc026fc139eecb67f1b79a2ff818..a39b93af48cd90624becc5236d5d0e05a703a955 100644 --- a/src/data/hptimelinedata.tsx +++ b/src/data/hptimelinedata.tsx @@ -453,7 +453,7 @@ export const timelinedata: Array<TimelineDatenpunkt> = [ <img src="https://static.igem.wiki/teams/5247/photos/hp/proandcon-png.svg"></img> </div> <div className="col"><p>We invited Max, our CF patient contact, to join Dr. Olariu in discussing the intersection of academic research, clinical application, and patient needs. Through our connection with <a href="https://www.cfvww.org" >CF Vests Worldwide</a>, an organization dedicated to providing life-saving therapy vests to Cystic Fibrosis patients globally, we gained insights into the challenges faced by CF patients, particularly in regions like Thailand, where access to advanced treatments and medical devices is limited. The conversation highlighted the critical role of early diagnosis and intervention, as well as the quality-of-life challenges many patients endure due to conventional treatments that may not be effective for everyone. Innovative approaches, such as our SORT LNP (lipid nanoparticle) delivery system, present promising alternatives for CF therapy. This system, which allows for RNA encapsulation and administration via dry spray inhalation, could revolutionize treatment by targeting lung cells more effectively, particularly in resource-limited settings. Dr. Olariu underscored the need for psychological support and coordinated care for CF patients, emphasizing that novel therapies like LNP-based gene treatments have the potential to improve treatment efficacy and accessibility, ultimately reducing the lifelong burden of care for patients and their families. </p> - <p>We have considered the extent to which an early diagnosis is always an advantage, as some parents perceive an early diagnosis as an additional burden and would prefer to experience the first years of their child's life without constant medical intervention. Especially when there are cases in which patients only show a clear clinical picture at an advanced age. The psychological burden also lies with the children, who often experience medical trauma because they are involved in such intensive medical care from birth. Additionally, the treatment of Cystic Fibrosis is very expensive, and the costs are covered by health insurance companies to varying degrees. In some countries, such as the USA, Ukraine or Developing countries, many families cannot afford the necessary treatments. But Dr. Olariu also drew our attention to another problem in the treatment of Cystic Fibrosis. Infections, especially with bacteria such as Pseudomonas spcc., are difficult to treat and often lead to long hospital stays. Max, our patients’ representative, who knows Dr. Olariu through his treatment, shared his experience with Pseudomonas spcc infections, illustrating the reality of an invisible danger that determines a patient's everyday life. Strict hygiene measures are required to prevent infections, such as wearing face masks in hospital and careful handling of potential sources of infection. The clinics where Cystic Fibrosis patients are treated work closely with a multidisciplinary team of doctors, psychologists, physiotherapists and nutritionists to ensure that patients receive holistic care. </p>, + <p>We have considered the extent to which an early diagnosis is always an advantage, as some parents perceive an early diagnosis as an additional burden and would prefer to experience the first years of their child's life without constant medical intervention. Especially when there are cases in which patients only show a clear clinical picture at an advanced age. The psychological burden also lies with the children, who often experience medical trauma because they are involved in such intensive medical care from birth. Additionally, the treatment of Cystic Fibrosis is very expensive, and the costs are covered by health insurance companies to varying degrees. In some countries, such as the USA, Ukraine or Developing countries, many families cannot afford the necessary treatments. But Dr. Olariu also drew our attention to another problem in the treatment of Cystic Fibrosis. Infections, especially with bacteria such as Pseudomonas spcc., are difficult to treat and often lead to long hospital stays. Max, our patients’ representative, who knows Dr. Olariu through his treatment, shared his experience with Pseudomonas spcc infections, illustrating the reality of an invisible danger that determines a patient's everyday life. Strict hygiene measures are required to prevent infections, such as wearing face masks in hospital and careful handling of potential sources of infection. The clinics where Cystic Fibrosis patients are treated work closely with a multidisciplinary team of doctors, psychologists, physiotherapists and nutritionists to ensure that patients receive holistic care. </p> </div> </div>], implementation: [<p>In summary, our project greatly benefited from the conversation with Dr. Olariu. His insights into the complexities of Cystic Fibrosis treatment, particularly the significance of early diagnosis, were invaluable and we considered early treatment methods. Max’s personal experiences added a human perspective, illustrating the medical and psychological challenges he faces, including infections with <i>Pseudomonas spp.</i> Dr. Olariu highlightend the importance of a multidisciplinary approach, involving not just medical professionals but also psychologists, physiotherapists, and nutritionists for holistic care. This discussion helped us appreciate the balance between timely interventions and the emotional burden on patients and their families, guiding us to develop a more empathetic understanding of living with Cystic Fibrosis.</p>], @@ -563,7 +563,7 @@ export const timelinedata: Array<TimelineDatenpunkt> = [ interviewtabid: "michaela", cardtext: "", language: "de", - quote: "x", + quote: "The use of primary cultures in research represents the first step toward clinical studies. Your approach is innovative, as we have never undertaken something like this before.", aimofcontact: "Our primary goal in reaching out to her was to gain insights into optimizing cell culture media, explore potential sponsorship opportunities for our project, and seek expert advice on handling primary cells in the lab.", insights: "Throughout our multiple discussions, she offered detailed advice on selecting and optimizing cell culture media for our specific needs, while also connecting us with opportunities for sponsorship. Later in the project, she provided technical guidance on the cultivation and handling of primary cells, ensuring that we followed best practices for cell culture.", implementation: "Based on her feedback, we refined our approach to cell culture media, enhancing our experimental workflows.Her technical support, as well as the support of Julia Watson helped us to establish our experiments in cellculture. Additionally, her advice was critical during the transition to primary cell culture, helping us secure the necessary resources and expertise for our experiments.",