From b340baa4ba0c26b6b7aa5bc62c2dea8aaa008149 Mon Sep 17 00:00:00 2001
From: Anna Baack <anna-lena.baack@uni-bielefeld.de>
Date: Thu, 26 Sep 2024 22:09:18 +0000
Subject: [PATCH] Bild in methods (Ohne zu trollen)
---
src/contents/methods.tsx | 2 +-
1 file changed, 1 insertion(+), 1 deletion(-)
diff --git a/src/contents/methods.tsx b/src/contents/methods.tsx
index db91407d..d8005c32 100644
--- a/src/contents/methods.tsx
+++ b/src/contents/methods.tsx
@@ -15,7 +15,7 @@ export function Methods() {
<H4 text="Principles of the patch clamp technique"></H4>
<p>Patch clamp recording involves the use of a glass micropipette which is manufactured from a glass capillary through the use of a Micropipette Puller. The micropipette is then filled with an electrolyte solution, which is subsequently brought into contact with the cell membrane. By applying gentle suction, a high-resistance seal called giga seal is formed between the pipette tip and the membrane patch. This enables the measurement of ionic currents with minimal noise interference [3]. Whole-Cell Configuration records currents from the entire cell by rupturing the membrane patch, accessing the intracellular environment, and is useful for analysing overall ion channel activity and cellular responses. Single-Channel Recording measures currents through individual ion channels without rupturing the membrane, enabling high-resolution study of channel conductance, gating, and selectivity [2].</p>
//TODO: Video Einfügen
- <p>The success of patch clamp experiments heavily depends on the composition of the solutions used. Typically, two main types of solutions are employed: The Pipette Solution in the micropipette mimics the intracellular environments, while the Bath Solution surrounds the cell and usually contains components that replicate the extracellular environment. Both solutions are meticulously designed to reflect the physiological conditions under which the cells operate, thereby ensuring that the measurements accurately reflect ion channel activity in a natural setting [2].</p><img src="https://static.igem.wiki/teams/5247/photos/for-wiki-texts/meth-patch-clamp/bild-meth-patch-clamp.png" text="Patch clamp setup"></img>
+ <p>The success of patch clamp experiments heavily depends on the composition of the solutions used. Typically, two main types of solutions are employed: The Pipette Solution in the micropipette mimics the intracellular environments, while the Bath Solution surrounds the cell and usually contains components that replicate the extracellular environment. Both solutions are meticulously designed to reflect the physiological conditions under which the cells operate, thereby ensuring that the measurements accurately reflect ion channel activity in a natural setting [2].</p>
<figure>
<img src="https://static.igem.wiki/teams/5247/photos/for-wiki-texts/meth-patch-clamp/bild-meth-patch-clamp.png" alt="Patch clamp setup"/>
<figcaption>Patch clamp setup</figcaption>
--
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