From 360281dcf477ca3f5702879e239a7233aa1ffe4e Mon Sep 17 00:00:00 2001
From: Liliana Sanfilippo <lsanfilippo@techfak.uni-bielefeld.de>
Date: Tue, 3 Dec 2024 16:33:12 +0100
Subject: [PATCH] q13
---
src/contents/description.tsx | 6 +++---
1 file changed, 3 insertions(+), 3 deletions(-)
diff --git a/src/contents/description.tsx b/src/contents/description.tsx
index a20e44b..e2a0db1 100644
--- a/src/contents/description.tsx
+++ b/src/contents/description.tsx
@@ -57,9 +57,9 @@ export function Description() {
</Section>
<Section title="Cystic Fibrosis" id="Cystic Fibrosis">
<Subesction title="Overview" id="Cystic Fibrosis1">
- <p data-aos="zoom-y-out" >Cystic Fibrosis (CF) is a common life-limiting genetic disorder, particularly affecting the Caucasian population, with approximately <b>162,400 people worldwide</b> living with the condition<SupScrollLink label="4"/>{/* ehem7 */}. Statistically, about <b>one in every 3,300</b> white newborns is born with CF <SupScrollLink label="5"/>{/*ehem8*/} . And according to the German Cystic Fibrosis Registry, the average life expectancy for children born with CF in 2021 was around 57 years <SupScrollLink label="6"/>{/*ehem9*/} , highlighting the severe and life-shortening nature of the disease. </p>
- <p>The modern understanding of CF dates back to 1922 when Dr. Dorothy Andersen, a pediatric specialist, first described the disease and coined the term "Cystic Fibrosis"<SupScrollLink label="7"/>{/*ehem10*/}. In Germany, it is commonly known as "Mukoviszidose," derived from the Latin words meaning "mucus" and "viscous" <SupScrollLink label="7"/>{/*ehem10*/} , emphasizing the characteristic thick, sticky mucus that defines the condition <SupScrollLink label="8"/>{/*ehem11*/}. </p>
- <p>Genetic research has identified over 1,700 mutations in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene, with the F508del mutation being the most common, affecting about 70% of CF patients. This mutation prevents the proper folding of the CFTR protein, significantly impairing its function <SupScrollLink label="13"/> . </p>
+ <p data-aos="zoom-y-out" >Cystic Fibrosis (CF) is a common life-limiting genetic disorder, particularly affecting the Caucasian population, with approximately <b>162,400 people worldwide</b> living with the condition<SupScrollLink label="4"/>{/* ehem7 */}. Statistically, about <b>one in every 3,300</b> white newborns is born with CF <SupScrollLink label="5"/>{/*ehem8*/}. And according to the German Cystic Fibrosis Registry, the average life expectancy for children born with CF in 2021 was around 57 years <SupScrollLink label="6"/>{/*ehem9*/} , highlighting the severe and life-shortening nature of the disease. </p>
+ <p>The modern understanding of CF dates back to 1922 when Dr. Dorothy Andersen, a pediatric specialist, first described the disease and coined the term "Cystic Fibrosis"<SupScrollLink label="7"/>{/*ehem10*/}. In Germany, it is commonly known as "Mukoviszidose," derived from the Latin words meaning "mucus" and "viscous" <SupScrollLink label="7"/>{/*ehem10*/}, emphasizing the characteristic thick, sticky mucus that defines the condition <SupScrollLink label="8"/>{/*ehem11*/}. </p>
+ <p>Genetic research has identified over 1,700 mutations in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene, with the F508del mutation being the most common, affecting about 70% of CF patients. This mutation prevents the proper folding of the CFTR protein, significantly impairing its function <SupScrollLink label="9"/>{/*ehem13*/}. </p>
<p>The CFTR protein regulates the flow of chloride ions across the membranes of cells in the lungs, digestive system, and other organs. This ion flow is essential for drawing water into surrounding tissues, which helps maintain the proper hydration and consistency of mucus. In patients with CF, the disruption of this process prevents sufficient water from entering the mucus, making it abnormally thick and sticky. The accumulation of this mucus leads to an obstruction of airways and digestive ducts, resulting in chronic lung infections, inflammation, impaired digestion, and malnutrition<SupScrollLink label="14"/> . </p>
<OneFigure
pic1="https://static.igem.wiki/teams/5247/project-description/lung-ephitel-biorender.png"
--
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