
Coding
Part:BBa_K3851000
Designed by: Max Swann Group: iGEM21_Baltimore_BioCrew (2021-08-28)
TPH1 gene from Homo sapiens codon-optimized for E. coli
The TPH1 gene in humans uses L-tryptophan to produce 5-HTP, the biochemical precursor to serotonin. Serotonin reduces the effects of depression and anxiety. Increased expression levels of TPH1 can alleviate or eliminate depressive symptoms, but a negative feedback loop is recommended to prevent over-expression.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
None |