Worldshaper-HZBIOX
Collaboration
Overview:
As a high school team that participated in the iGEM
competition in the first year, we had actively cooperated and communicated
with other teams. Not only the process finding the collaboraters but also
discussing the proper collaborated proposals, we learned a lot. Our
collaboration this year involves six aspects:
1 Co-host online public engagement activity
2 Gut alliance: cohost online lecture
3 Cohost public engagement activity in biology training
camp
4 Cohost a virtual meetup
5 Long-term partnerships with LZU-China
6 Attend online meetup and CCIC 9
1 Co-host online public engagement
activity
On July 10, we had an online publishing event with
Worldshaper-HZ, Worldshaper-Shanghai,
Worldshaper-Nanjing, Worldshaper-NJBIOX, Ivymaker-China and GYHS. The seven
teams held a Tencent conference together and streamed it on WeChat Channels.
Our team worked as a moderator, wrote the moderator script, and supported the
teams in researching the sequence. Worldshaper-HZ was responsible for creating
the posters, and Worldshaper-Shanghai was responsible for the live-streaming
promotion.
With the theme of synthetic biology in life, this online
event is divided into four parts, including
introduction of synthetic biology and its applications in
environmental protection, cancer detection methodologies, disease treatment,
and food satety. During the conference, the seven teams
have
•
Discussed and shared how we applied synthetic
biology
•
Introduced the teams we are working with
•
exchanged our current progress.
We and
Worldshaper-Shanghai are responsible for the Disease
Treatment part. In this section, we briefly explained
what colon cancer is and shared some information about ECN 1917, the probiotic
we used. At the same time, popularize the early symptoms of colon cancer and
call on to pay more attention to their own body.
2 Gut
alliance: cohost of online lecture
This year, our team (Worldshaper_HZBIOX)
collaborated with HS-CHINA, LZU-CHINA, LZU-HS-PRO-A, NEU-CHINA, and
NWU-CHINA-A and set up Gut Alliance of iGEM China. On August
14th, the six teams of Gut Alliance
co-hosted an online seminar from 2:00 to 4:30 p.m. In this activity, we
invited three experts as guests to the lecture, Canhui Lan from Warm Heart
Biotechnology Research Institute, Daixu Wei from Department of Life Science
and Medicine, Northwestern University, and Xiaojuan Dong from The Fifth
People’s Hospital of Shaanxi Province.
All teams aimed to focus on the intestinal health in public
from the perspectives of college and high school students, making people
more familiar with the intestine through the popularization of various gut microbiota-related
topics. The member from our team, for instance, introduced the association
between sugar substitute and gut microbiota, bringing detailed and
professional introduction of sugar substitute and its drawbacks to warn people
about the significance of consuming less low-sugar drinks containing
aspartame. Moreover, we were responsible for organizing each
team’s presentation topic and making brochure after the theme
lecture.
3
Cohost public engagement activity in biology training
camp
On July
21st, our team
collaborated with Worldshaper-HZ made a project share towards 20
students who attended a 7-day biology summer camp in the
laboratory. We made the presentation about our project
respectively. From our background
investigation, experimental prospect, experimental process to the practical
significance of the experimental results. Students from the Biological Camp
also had a preliminary understanding of our project, and also realized the
high incidence of intestinal cancer and the inadequacy of current treatment
effect. I believe they also feel the significance and importance of this
project.
4
Cohost a virtual Meetup
On September 10, Worldshaper-HZBIOX and Worldshaper-SH
cooperated to organize an academic exchange event. The participating teams
were BS-united-China (Hainan), LZU-HD-CHINA-B (Shanghai), XHD-Wuhan-Pro-China
(Wuhan), NMU-China (Shanghai), BIT-China (Beijing), NNU-CHINA (Nanjing), and
LZU-HD-Pro-B.
In this event, our team helped
Worldshaper-Shanghai team to improve the planning
plan and clarify many uncertain details. Our team also helped to make the PPT
for the host, and our team's student Yu
Ninger acted as the host, and she controlled the pace of the
team very well. Also Worldshaper-HZBIOX invited Professor Wu Jiequn from
Zhejiang University of Technology as a judge. Our team, Wang Weifan, explained
the experimental results and principles of our project. After the sharing,
Prof. Wu made comments and improvement suggestions on our topic
:
need to prove that EcN is necessary to be cleaved and lysin is
necessary to be used. It is necessary to prove that EcN1917 is functional for
target targeting.
5
Long-term partnership with LZU-China
Our team finalized our partnership with
LZU-China in April because of the same topic about colonial treatment. We have
been keeping in touch for a long time and discussing and figuring out the
problems encountered. The areas we have been working together are as follows.
We are grateful for this experience of mutual help, and we have learned a lot
in this process. Please refer to Partnership page for details.
•
Wet lab: Lysin gene
improvement
•
Education and public engagements: a synthetic biology-themed picture book promoted in Hangzhou Low
Carbon Museum and Landa Elementary School, co-launched some pup-science
articles on the self-media, co-hosted public activity in Hangzhou low carbon
science and technology museum
•
Human practices:
information shared and subsequent improve our applied design
•
Model: give useful
suggestion for our model
•
Applied design:
explore applied design and constantly improve it
6
Attend online meetup and CCIC 9
In addition, our team also participated in the online
meetup organized by iGEM China and the
9th China CCIC Conference.
On July 16 and 17, iGEM China hosted the
largest two-day online seminar this year. Twenty-seven teams from all
around China, including Guangxi University, Jiangnan University,
Northwestern Polytechnical University, and Jilin University, participated
in the Tencent conference. The purpose of this event was to promote the
iGEM competition, and at the same time to increase mutual connections and
understandings between the participating teams, to find the possibilities
for further collaboration.
During the meeting, each team introduced in
detail the background, research significance, innovative ideas, and HP
achievements of their project.
On this meetup,
we introduced our
project which is how arginine-engineered probiotics can be used for
colorectal cancer immunotherapy. We talked about the background of this
project and topic, why we’re researching this, the basic principles,
and more!
As a high school team, we learned a lot from the exchange
and sharing with other undergraduate teams, which also inspired us to better
design our projects and better understand the iGEM competition.