diff --git a/pages/model.vue b/pages/model.vue index 961968938027a159b3cb341b2675f4967d509d67..3f0d8023e24ef43ceb0990bf579ea5e1cd3b5765 100644 --- a/pages/model.vue +++ b/pages/model.vue @@ -328,33 +328,33 @@ <p>One of the primary uses of oxDNA, apart from origami DNA structure visualization, is hairpin formation. We obtained the trajectories, tertiary structures, and energy files for each of the hairpin probes used in our project. By setting the temperature to 25 <sup>o</sup>C. You can observe that each probe has the expected loop structure and the two hanging tails, one for target detection and one for binding to the DNA backbone. Equilibration was achieved in 10<sup>8</sup> steps.</p> <div class="gallery grid4"> <figure class="gallery"> - <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig1-step2.png"><img src="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig1-step2.png"/></a> - <figcaption class="figure-caption text-left"><span>Fig.3:</span> Domain order of H2 hairpin probe</figcaption> + <figcaption class="figure-caption text-left">hsa_circ_0070354 H1 Probe</figcaption> + <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/probes/h1-7035.png"><img src="https://static.igem.wiki/teams/4118/wiki/probes/h1-7035.png"/></a> </figure> <figure class="gallery"> - <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"><img src="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"/></a> - <figcaption class="figure-caption text-left"><span>Fig.4:</span> Reaction breakdown of H1 and H2 hybridization </figcaption> + <figcaption class="figure-caption text-left">hsa_circ_0005962 H1 Probe </figcaption> + <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/probes/h1-5962.png"><img src="https://static.igem.wiki/teams/4118/wiki/probes/h1-5962.png"/></a> </figure> <figure class="gallery"> - <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"><img src="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"/></a> - <figcaption class="figure-caption text-left"><span>Fig.4:</span> Reaction breakdown of H1 and H2 hybridization </figcaption> + <figcaption class="figure-caption text-left">hsa_circ_0102533 H1 Probe </figcaption> + <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/probes/h1-2533.png"><img src="https://static.igem.wiki/teams/4118/wiki/probes/h1-2533.png"/></a> </figure> </div> <div class="gallery grid4"> <figure class="gallery"> - <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig1-step2.png"><img src="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig1-step2.png"/></a> - <figcaption class="figure-caption text-left"><span>Fig.3:</span> Domain order of H2 hairpin probe</figcaption> + <figcaption class="figure-caption text-left">hsa_circ_0070354 H2 Probe </figcaption> + <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/probes/h2-7035.png"><img src="https://static.igem.wiki/teams/4118/wiki/probes/h2-7035.png"/></a> </figure> <figure class="gallery"> - <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"><img src="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"/></a> - <figcaption class="figure-caption text-left"><span>Fig.4:</span> Reaction breakdown of H1 and H2 hybridization </figcaption> + <figcaption class="figure-caption text-left">hsa_circ_0005962 H2 Probe </figcaption> + <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/probes/h2-5962.png"><img src="https://static.igem.wiki/teams/4118/wiki/probes/h2-5962.png"/></a> </figure> <figure class="gallery"> - <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"><img src="https://static.igem.wiki/teams/4118/wiki/website-assets/model/fig2-step2.png"/></a> - <figcaption class="figure-caption text-left"><span>Fig.4:</span> Reaction breakdown of H1 and H2 hybridization </figcaption> + <figcaption class="figure-caption text-left">hsa_circ_0102533 H2 Probe </figcaption> + <a width="100%" href="https://static.igem.wiki/teams/4118/wiki/probes/h2-2533.png"><img src="https://static.igem.wiki/teams/4118/wiki/probes/h2-2533.png"/></a> </figure> </div> - <figcaption class="figure-caption text-left"><span>Fig.10. Circular DNA template conformations:</span> In the left the initial structure is depicted, and in the right the formed padlock template is shown. With green RCA primer is shown and with black the phosphorylated DNA template.</figcaption> + <figcaption class="figure-caption text-left"><span>Fig.11 H1 and H2 probe tertiary structures are depicted for each circRNA.</span> For the H1 probes the BSJ detection site is colored in black and the RCA binding domain in blue. Regarding the H2 probe the RCA binding domain is colored in blue and the H1 binding site in green</figcaption> </section> <section> <h3 class="small-title">Nanostructure formation</h3>